2013 Cambridge GOC Scientific Advisory Board Meeting Agenda

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  • The morning session will include reports from GO Directors.
  • GOC community is encouraged to attend the morning session.
  • SAB will have private catered lunch at 12:30 in the main meeting room.
  • Afternoon session will include SAB and GOC Directors and sub-contract PIs

Morning SAB Meeting (Open)

GOC SAB 2013

  • Gary Bader, University of Toronto
  • Matt Hibbs, Trinity University
  • John Hogenesch, University of Pennsylvania
  • Andrew Su, Scripps Research Institute
  • Simon Tavare, University of Cambridge
  • Mike Tyers, University of Montreal

8:30AM Introductions and Overview of GOC - Mike

9:00AM -Annotation - Paul S

  • Handout: Annotation stats
  • Community Curation
    • Transcription factor
    • CANTO S. pombe (Val)
  • Common Annotation tool
    • protein2GO transition (Kimberly)
  • Phylogenetic based - PAINT (Paul T.) & JsPaint (Seth)
  • Summary: Key Accomplishments & timeline for next steps

10:00am - Ontology domain & modeling extensions - Judy & Paul T

  • Handout: Ontology production stats
  • Domain specific development
    • Crossproducts and ChEBI alignment
    • Apoptosis
    • Cell cycle
  • Modeling enhancements
    • Transition to OWL
    • Logical definitions (TermGenie)
    • Annotation Extensions
    • LEGO
  • Summary: Key Accomplishments & timeline for next steps

11:00 - break

11:30 - Community Resource - Suzi

  • Handout: usage stats
  • GO Mine
  • GO Galaxy
  • New website prototype
  • AmiGO 2 and Solr
  • Summary: Key Accomplishments & timeline for next steps

12:30PM -- Private lunch for SAB

Questions for SAB

  1. How much effort should we devote to engaging user community about GO resources and how to most effectively use them?
  2. What is appropriate balance between curation of experimental annotations (mostly in MODs) with increased context of specific protein, specific cell type, specific time, and the curation of inferential annotations for all life forms via phylogenetic/comparative approaches?
  3. What GOC tasks have greatest impact on scientific usability?
  4. Is balance of effort between ontology development and knowledge curation and usability appropriate?
  5. How can the LEGO style curation be used most effectively?
  6. How might we best achieve broad use of the common annotation tool?
  7. How cam we increase community involvement in ontology development and annotation?
  8. How to prioritize the families for PAINT curation?

1:30PM Discussion: SAB, PIs

  • Summary, Wrap-UP at end of afternoon