Annotation Conf. Call 2018-04-10

Agenda

GOC Meeting, NYU, New York, NY, May 12-14th

• Reminder to register, and reserve your hotel room before April 6th if staying at the Shelburne NYC
• Logistics
• Agenda

20th Anniversary GO Meeting, Montreal, Canada

• Dates set for Oct 17-19

Annotation Survey

• We are conducting a survey on annotation practices across the GOC
• This will allow us to have a better overall view of different group's workflows, pipelines
• Only need one response per annotation group
• Would like results before the GOC meeting in NY
• Please could each group respond by May 1st

Updates on Projects

MAPK Cascade

• MAPK cascade- Signaling Project

Extracellular Matrix

• Extracellular matrix revisions
  • proposal

Canonical Wnt Signaling Pathway

• Working on compiling annotations to review
• Main issues:
  • Distinguishing gene products that are involved in canonical Wnt signaling vs +/- regulation of canonical Wnt signaling
  • Annotating to more granular child of Wnt signaling pathway when appropriate
  • Annotation of downstream targets to the canonical Wnt signaling pathway

Ontology Development and Annotation Review

Transcription factor refactoring

• Remove the 'transcription factor activity, protein binding' branch
  • https://github.com/geneontology/go-ontology/issues/15535
  • Obsoletion notice: Some children of GO:0000988 transcription factor activity, protein binding’
  • https://github.com/geneontology/go-ontology/issues/15538

Annotation Review requests

• GO:0000989 'transcription factor activity, transcription factor binding'
  • https://github.com/geneontology/go-annotation/issues/1926
• GO:0001076 'transcription factor activity, RNA polymerase II transcription factor binding'
  • https://github.com/geneontology/go-annotation/issues/1927

• There will be more annotations reviews to come in the upcoming days/weeks. For most the work load is expected to be small, a few proteins per group at the most.

• Please let Pascale know if you are trying to annotate a function and cannot find the term - this will help decide whether some terms are missing or if we need to improve some term labels/definitions.

GO-CAM/Noctua

• Next call tomorrow, Wednesday, April 11th at 11:00am EDT (see Google calendar)

Protein Complexes Working Group

• Next call on Monday, April 23rd at 1:10pm EDT (see Google calendar)

Minutes

• On call: Chris, David H., Dustin, Harold, Helen, Karen, Kimberly, Li, Midori, Pascale, Paul T., Penelope, Petra, Sabrina, Sage, Stan, Suzi A., Tanya, Tom, Val