Annotation Extension Relation:has indirect input
Identifies an entity indirectly affected (bound, transported, modified, consumed or destroyed) by the gene product's participation in a Molecular Function or Biological Process.
If the entity is directly bound/acted upon by the gene product that is the subject of the annotation, then the relation: has_direct_input should be alternatively considered.
Scope of use
BFO:0000007 ! process (Biological Process or Molecular Function)
ENTITY_UNION:0000005 ! chemical, gene product, or complex
Annotation Extension Usage Examples
1. PMID:11278723 (Fig 3a) Overexpression of JIK increases the phosphorylation of TRAF2 (Q12933).
JIK (Q9H2K8) should be annotated to;
col 5: GO:0006468 ! protein phosphorylation col 16: has_indirect_input(Q12933)