Annotation Extension Relation:results in division of

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Definition

The relationship linking a entity and its participation in a process that results in the division of the entity into two entities of the same type.

Comment

Example of use: an annotation of gene X to cell division with results_in_division_of CL:0000057 (fibroblast) means that at the end of the process a single fibroblast has divided into two fibroblasts.

Child terms

  • None.

Scope of use

Domain

GO:0003674 (molecular_function) or GO:0008150 (biological_process)

Range

CL:0000000 (cell) or WBbt:0004017 (cell)

Annotation Extension Usage Examples

1. Gata3 is required for reactive proliferation of radial glial cells in telencephalon of adult zebrafish

Paper: "Regenerative Neurogenesis from Neural Progenitor Cells Requires Injury-Induced Expression of Gata3" (PMID: 23168169)

Statement from paper: "... knocking down gata3 reduces the number of injury-stimulated proliferation [of radial glial cells] at 3pdl significantly, to the level characteristic for unlesioned telencephalon."

Gene Name (col 2) GO ID (col 5) Reference (col 6) Evidence (col 7) Annotation Extension (col 16) Parent terms of new folded GO term
Unfolded Q91428 Gata3 GO:0008284 positive regulation of cell proliferation PMID: 23168169 IMP results_in_division_of (CL:0013000 forebrain radial glial cell)
Folded Q91428 Gata3 New GO ID positive regulation of forebrain radial glial cell proliferation PMID: 23168169 IMP is_a new GO: positive regulation of radial glial cell proliferation, is_a child of GO:0008284 positive regulation of cell proliferation

OWL class expression: GO:0008284 positive regulation of cell proliferation results_in_division_of SOME CL:0013000 forebrain radial glial cell

2. Pax6a and Pax6b are required during neuronal progenitor proliferation in retina of adult zebrafish

Paper: "Pa6a and Paxb are required at different points in neuronal progenitor cell proliferation during zebrafish photoreceptor regeneration" (PMID: 20152834)

Statement from paper: "...knockdown of Pax6b expression inhibited the subsequent division of the Müller glia-derived INL neuronal progenitor. In contrast, reduction of Pax6a expression allowed this initial neuronal progenitor cell division, but it prevented later cell divisions."

Gene Name (col 2) GO ID (col 5) Reference (col 6) Evidence (col 7) Annotation Extension (col 16) Parent terms of new folded GO term
Unfolded P26630 Pax6a GO:0008284 positive regulation of cell proliferation PMID: 20152834 IMP results_in_division_of (CL:0002672 retinal progenitor cell)
Folded P26630 Pax6a New GO ID positive regulation of retinal progenitor cell proliferation PMID: 20152834 IMP is_a GO:0008284 positive regulation of cell proliferation

OWL class expression: GO:0008284 positive regulation of cell proliferation results_in_division_of SOME CL:0002672 retinal progenitor cell

Gene Name (col 2) GO ID (col 5) Reference (col 6) Evidence (col 7) Annotation Extension (col 16) Parent terms of new folded GO term
Unfolded Q6DHA8 Pax6b GO:0008284 positive regulation of cell proliferation PMID: 20152834 IMP results_in_division_of (CL:0002672 retinal progenitor cell)
Folded Q6DHA8 Pax6b New GO ID positive regulation of retinal progenitor cell proliferation PMID: 20152834 IMP is_a GO:0008284 positive regulation of cell proliferation

OWL class expression: GO:0008284 positive regulation of cell proliferation results_in_division_of SOME CL:0002672 retinal progenitor cell



Back to Annotation usage examples for each annotation extension relation