Annotation Extension Relation:results in specification of

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Definition

The relationship linking a cell and its participation in a Molecular Function or Biological Process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.

Comment

Synonyms

Child terms

  • None

Scope of use

Domain

BFO:0000007 ! process (Biological Process or Molecular Function)

Range

CL:0000000 ! cell

Annotation Extension Usage Examples

Indicating the cell or cell type specified by the activity of a gene product

Statement from paper:

However, the strong loss-of-function allele of eya-1, ok654 (Furuya et al., 2005), displayed M lineage phenotypes similar to ceh-34(RNAi-P): loss of M-derived CCs and variable loss of embryonic CCs (Table 1, Fig. 3A). Thus, both ceh-34 and eya-1 are required for specifying the embryonic and M-derived CCs.

Note that in the above sentence, M refers to the M mesoblast and CCs refers to coelomocytes.

Gene Name (col 2) GO ID (col 5) Reference (col 6) Evidence (col 7) With (col 8) Annotation Extension (col 16)
Q94165 ceh-34 GO:0007501 mesodermal cell fate specification PMID:19427847 IMP WB:WBRNAi00101780 results_in_specification_of(WBbt:0005751 coelomocyte)
O17670 eya-1 GO:0007501 mesodermal cell fate specification PMID:19427847 IMP WB:WBVar00091938 results_in_specification_of(WBbt:0005751 coelomocyte)

Using examples to demonstrate Folding_and_Unfolding using the relationship results_in_specification_of

Indicating the cell or cell type specified by the activity of a gene product

Statement from paper:

However, the strong loss-of-function allele of eya-1, ok654 (Furuya et al., 2005), displayed M lineage phenotypes similar to ceh-34(RNAi-P): loss of M-derived CCs and variable loss of embryonic CCs (Table 1, Fig. 3A). Thus, both ceh-34 and eya-1 are required for specifying the embryonic and M-derived CCs.


Folded/unfolded Gene Name (col 2) GO ID (col 5) Reference (col 6) Evidence (col 7) With (col 8) Annotation Extension (col 16) Parent terms of new folded GO term
Unfolded Q94165 ceh-34 GO:0007501 mesodermal cell fate specification PMID:19427847 IMP WB:WBRNAi00101780 results_in_specification_of(WBbt:0005751 coelomocyte)
Unfolded O17670 eya-1 GO:0007501 mesodermal cell fate specification PMID:19427847 IMP WB:WBVar00091938 results_in_specification_of(WBbt:0005751 coelomocyte)
Folded Q94165 ceh-34 GO:0007501 mesodermal cell fate specification resulting in specification of coelomocyte PMID:19427847 IMP WB:WBRNAi00101780 is_a mesodermal cell fate specification
Folded O17670 eya-1 GO:0007501 mesodermal cell fate specification resulting in specification of coelomocyte PMID:19427847 IMP WB:WBVar00091938 is_a mesodermal cell fate specification


OWL class expression:


OWL class expression: GO:0007501 mesodermal cell fate specification results_in_specification_of SOME WBbt:0005751 coelomocyte



Back to Annotation usage examples for each annotation extension relation