Annotation consistency: chaperone activity definition

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Group Members

(anyone can add themselves)

  • Victoria Petri, Ruth Lovering, Jennifer Deegan, Val Wood

Proposed solution(s)

Clarify the definitions of unfolded/misfolded protein binding and add chaperone activity as a synonym to both of the terms. Also add ‘de novo’ synonym to ‘unfolded protein binding’.

Reinstate chaperone activity as a function for a protein that folds/stabilises other proteins. Transport etc functions need to be removed from the original definition.

Comments/counter arguments

several closed SF items, this one recently opened: http://sourceforge.net/tracker/index.php?func=detail&aid=2136864&group_id=36855&atid=440764

Proposed resolution

Ontology development required

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