Creating a Regulation Term
From GO Wiki
See Ontology_Editors_Daily_Workflow for creating branches and basic Protégé instructions.
- To create a ‘positive regulation of x’ or ‘negative regulation of x’ term, the parent ‘regulation of x’ term must first be created.
- To create a parent regulation term, make sure the ‘Asserted view’ is active (not the ‘Inferred view’).
- In the 'Protege classes view', navigate to ‘biological regulation’.
- Click on the add subclass button at the top left corner.
- In the pop-up window add the name of the new regulation term ‘regulation of target process’. The identifier should auto-populate. Click the button to add the term.
- Enter the appropriate information for namespace, definition, synonyms, etc. in the obo editing view as described in the ‘Creating a New Ontology Term’ Section.
- Standard definitions for regulation terms:
- Regulation: Any process that modulates the frequency, rate or extent of [process]
- Positive regulation: Any process that activates or increases the frequency, rate or extent of [process]
- Negative regulation: Any process that stops, prevents or reduces the frequency, rate or extent of [process]
- Create a logical definition for the term: biological regulation and regulates some target process.
- Remove the asserted ‘biological regulation’ parent.
- Run the reasoner to be sure that reasoning results in the correct inferred parents.
- Save changes.
See Ontology_Editors_Daily_Workflow for commit, push and merge instructions.
Last reviewed: May 24, 2017 Back to: Ontology Editing Guide