Draft organization of ideas
From GO Public
Contents |
Issues raised by signaling discussion
Note this is draft page. The idea is that each aspect is commented on separately, please do not write one long pieces of text which addresses all of these points, but write suggestions under the relevant section only.
Introduction
Generic signaling A real example
Light approaching a plant shoot from the side causes bending.
- 1) Light exits the sun or a light bulb.
- 2) The light travels through space and hits one side of a plant.
- 3) The light is absorbed by a photoreceptor at the tip of the plant, on only one side of the plant.
- 4) A message is sent from the photoreceptor via auxin to a place a centimetre down from the tip of the shoot, on the other side of the shoot from where the light was absorbed.
- 5) The auxin signal arrives at its destination and is registered in the region that will respond.
- 6) Cells on the side of the shoot away from the light that have received the auxin signal elongate to make the shoot bend toward the light.
Discussion Topics
Statements from SF or minutes to be sorted into specific items
- Should there be a GO term which covers all points in generic signaling example from 1 to 6, bearing in mind that the signal in many cases is produced by the organism itself?
- Alex points out that: signaling is necessarily a linked process from start to finish. However, when scientists study signals, they rarely study the entire process in a single experiment, and any evidence that a signal has been produced or transmitted is not necessarily evidence that it will be received and interpreted.
- David, 2006 SF item: It seems to me that hormone secretion is a part of hormonal signaling.
- Val SF request: S. pombe has 3 MAPK cascades, mating pheromone responsive MAPK cascade(sensu Fungi) not yet created GO:0031098 stress-activated protein kinase signaling pathway, parents: is_a GO:0033554 cellular response to stress and is_a GO:0007242 intracellular signaling cascade cell integrity MAPK cascade (sensu Fungi) not yet created but related term exists GO:0000196 MAPKKK cascade during cell wall biogenesis, parents: part of GO:0042546 cell wall biogenesis and is_a GO:0000165 MAPKKK cascade
