Immunologically Important Genes Listed by Priority Score

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Explanation of Gene Prioritization


Genes with Priority Score of 16


TLR4


Genes with Priority Score of 15


IL10 TNF


Genes with Priority Score of 14


CCL2 IL6 MAPK14


Genes with Priority Score of 13


IFNB1 IL4 LCK NFKB1 PTPRC SPP1 TLR2 ZAP70
IL2 IL6ST


Genes with Priority Score of 12


B2M CD14 FYN IFNG IL12B IL1R1 IL2RA STAT3
C3 CXCL12 HLA-DQB1 IKBKG


Genes with Priority Score of 11


ADA CASP8 CD8A CTLA4 FAS IKBKAP ITGAM NFKBIA
BCL2 CCR7 CHUK CXCR3 FCGR2B IL1B ITGB2 RELA
C5 CD28 CLU CXCR4 HLA-DRA IL2RG MYD88 TGFB1
CASP3 CD4 CSF1R DPP4 ICAM1 IL7


Genes with Priority Score of 10


AIRE CASP2 CD44 GZMA IKBKE IRF1 STAT1 TLR1
APP CCL5 CD74 HLA-A IL13 ITGAX STAT2 TNFRSF1B
C1QBP CCR2 CFB HLA-B IL1RN MASP2 STAT5B TNFSF11
C4A CCRL2 CFH HLA-C IL4R MS4A1 STAT6 TRAF5
C4B CD1D FCGR1A HLA-DQA1 IL6R RAG1 TCF7 TRAF6
CASP1 CD24 FCGR3A IKBKB IRAK1 SERPING1 TIRAP VCAM1
CASP10


Genes with Priority Score of 9


BAX CD79B CTSS HLA-DMA IL18 JAK1 PECAM1 THY1
BST1 CD82 CX3CR1 HLA-DMB IL18R1 LCP2 PPARG TLR3
BST2 CD83 CXCL10 HLA-DPA1 IL1R2 LILRB1 PSMB5 TLR5
C1QA CD86 CXCL2 HLA-DPB1 IL32 LILRB3 PSMB8 TLR9
C1R CD97 CYBB IFNAR1 IL5 MAPK1 RELB TNFRSF11A
C9 CEACAM1 DEFB1 IFNAR2 IL7R MBL2 SELE TNFRSF8
CCL20 CFD FADD IFNGR1 IL8RA MBP SLAMF7 TOLLIP
CD36 CLEC4E FCAR IGF2R IL8RB NCF4 SOCS3 TP53
CD40LG CR1 FN1 IL12A ITGA2B NFATC3 TAL1 TRAF1
CD55 CRADD FOXP3 IL15 ITGA4 NOTCH1 TAPBP TRAF2
CD7 CTSC HAMP IL16 ITGB1 PDGFRB TFRC TRAF3
CD79A CTSG


Genes with Priority Score of 8


ABCB1 CCL4 CD81 DEFB4 IL12RB1 KLRB1 NFATC1 SH2D1A
ABL1 CCR6 CD8B EBI2 IL13RA1 KLRC1 NFATC2 SIGIRR
AICDA CCR8 CD9 ENTPD1 IL17A KLRD1 NFIL3 SLAMF1
ARHGDIB CCRL1 CD96 FCER1A IL17B LAIR1 NFKB2 SOCS1
ATM CD164 CD99 FCER1G IL18RAP LIF NOS2A SRC
BCAP31 CD1A CDH5 FCGR2A IL1A LILRB2 PDCD1 STAT4
BCL3 CD2 CDKN1A FCGR3B IL1RAP LITAF PDCD2 STAT5A
BTK CD209 CEACAM6 FCGRT IL1RL1 LTA PDGFB SYK
C1QB CD22 CFI FKBP5 IL21 LTB4R PLAU TAP1
C1S CD244 CFP GNLY IL21R LTB4R2 PLAUR TAP2
C2 CD247 CIITA GP1BB IL23A LTBR PML TNFAIP6
C4BPA CD27 CISH GPI IL2RB LTF PRF1 TNFRSF10C
C6 CD34 CLEC4A GZMB IL3 LY96 PRKCD TNFRSF13B
C7 CD3D CLEC5A HFE IL8 MAP4K1 PSMB10 TNFRSF13C
C8A CD3E CMKLR1 HLA-DOB ILF3 MAP4K2 PSMB7 TNFRSF14
C8B CD3EAP CR2 HLA-DRB1 IRAK2 MAPK11 PSMB9 TNFRSF17
C8G CD40 CSF1 HLA-DRB3 IRF3 MARCO PSMC2 TNFRSF4
CAMP CD46 CSF2 ICAM2 IRF8 MASP1 PSMD7 TNFSF10
CCBP2 CD48 CSF2RB ICOS ITGA5 MIF PTAFR TNFSF12
CCL11 CD5 CSF3R IFI16 ITGA6 MME PTGS2 TNFSF13B
CCL15 CD53 CTNNB1 IFI35 ITGAL MR1 PTK2 TRAF4
CCL16 CD58 CX3CL1 IFIT2 JAK2 MSR1 PTPN22 VTN
CCL18 CD59 CXCL1 IFITM1 JAK3 MX1 PTPN6 XCL1
CCL19 CD6 CXCL13 IL10RA KIR2DL1 NCAM1 SELL XCR1
CCL22 CD80 DEFB103A IL11RA KIT NCR1 SELPLG ZEB1
CCL3


Genes with Priority Score of 7


A2M CCL8 CLEC2B GP1BA IL1F9 JUN NCR2 SEMA4D
ABCF1 CCND1 CLEC4M GP9 IL1RAPL1 KEL NFKBIB SEMA7A
ADAM10 CCR1 CLEC7A GYPA IL1RAPL2 KIR2DL2 NFKBIZ SFTPD
ADAM17 CCR4 CNR2 GYPB IL1RL2 KIR2DL3 NOD2 SIGLEC5
ADAR CCR5 CR1L GYPC IL20 KIR2DL4 NT5E SIGLEC6
AHR CD109 CREBBP GZMM IL20RA KIR2DS1 OLR1 SLC3A2
AKT1 CD151 CRLF2 HDAC1 IL22 KIR2DS2 PAFAH1B2 SLC4A1
ALCAM CD160 CRP HLA-DOA IL23R KIR2DS4 PAFAH1B3 SOCS4
APC CD163 CSF2RA HLA-DRB5 IL24 KIR3DL1 PDCD1LG2 SOD2
ARTS-1 CD177 CSF3 HLA-E IL25 KIR3DL2 PF4 SPN
AVPR1A CD180 CXCL11 HLA-F IL26 KLRC2 PLA2G4A SQSTM1
BAG4 CD19 CXCL14 HRH2 IL27 LAG3 PPARD TBK1
BATF CD1B CXCL16 HRH4 IL27RA LAT PPBP TBX21
BCAM CD1C CXCL3 ICAM3 IL28A LEPR PPIA TCF3
BCL6 CD1E CXCL5 ICOSLG IL28B LGALS1 PRKCA TCF7L2
BIRC3 CD207 CXCL6 IFI27 IL28RA LILRA1 PRNP TCIRG1
BSG CD226 CXCL9 IFIT1 IL29 LILRA2 PROCR TGFA
BTLA CD274 CXCR7 IFNA1 IL3RA LILRA3 PRSS16 THBS1
C1QC CD2AP DAP IFNA2 IL4I1 LILRB4 PSMC1 TLR7
C1QTNF5 CD300LF DAXX IFNA4 IL5RA LILRB5 PSMC3 TNFAIP3
C1RL CD33 DEFA1 IFNA8 IL9 LRP1 PSMD1 TNFRSF10A
C4BPB CD37 DEFA4 IGF2 IL9R LTB PSMD12 TNFRSF10B
C5AR1 CD38 DEFA5 IL10RB ILF2 LY86 PSME1 TNFRSF10D
CASP6 CD3G DEFA6 IL11 IRAK1BP1 LY9 PSME2 TNFRSF18
CASP7 CD47 EBF1 IL12RB2 IRAK3 MAP2K1 PSME3 TNFRSF9
CASP8AP2 CD52 EBF2 IL13RA2 IRAK4 MAP3K5 PSMF1 TNFSF14
CBL CD5L EDN1 IL15RA IRF2 MAP3K7 PTGER4 TNFSF4
CCL1 CD63 EGFR IL17C IRF5 MAP4K4 PTK2B TNFSF8
CCL13 CD68 ELA2 IL17D IRF7 MAPK3 PVRL1 TRADD
CCL14 CD69 ENG IL17F ISGF3G MEFV RAF1 TRPC4AP
CCL17 CD72 EPO IL17RA ITGA1 MICA RFX1 TTRAP
CCL21 CD84 EPX IL17RB ITGA2 MICB RHAG TYK2
CCL23 CDH1 F3 IL17RD ITGA3 MLL RHCE ULBP1
CCL24 CEACAM5 FASLG IL18BP ITGAD MPL RHD VAV1
CCL25 CEBPB FCER2 IL19 ITGAE MPO RIPK1 VEGFA
CCL26 CFHR1 FCGR2C IL1F5 ITGAV MRC1 S100A8 VPREB1
CCL27 CFLAR FOS IL1F6 ITGB3 MST1R SCARB1 XBP1
CCL28 CKLF FUT3 IL1F7 ITGB4 MYC SCYE1 XCL2
CCL3L1 CLEC10A FUT4 IL1F8 ITK NCF2 SELP XRCC5
CCL7


Genes with Priority Score of 6


ACVR1B CANX CYSLTR1 GATA3 ISG20 NCR3 PSMB6 SLAMF6
ADAM8 CASP5 DAP3 GBP1 ITGB7 NFKBIE PSMC4 SLC7A5
ADH5 CBLB DAPK1 GNE JUND NKTR PSMC5 SOCS2
ADORA2A CCR10 DARC GP5 KIR2DL5A NPPA PSMC6 SOD1
AFP CCR3 DDR1 GZMH KIR2DS5 NR3C1 PSMD13 SP110
ALOX5AP CCR9 DEFA3 HLA-DQB2 KIR3DL3 NRP1 PSMD2 SPARC
AMBP CD200 DEFB105A HLA-DRB4 KITLG NTF3 PSMD3 SPI1
APOE CD200R1 DEFB106A HLA-G KLRF1 OPRD1 PTEN ST6GAL1
ATRN CD276 DEFB119 HRAS KLRK1 ORM1 PTGES TCF1
BAD CD300E DEFB123 HRB KRT1 ORM2 PTGS1 TGFB2
BAT2 CD320 DMBT1 HSP90B1 LAIR2 OSM PTN TGFBR1
BCL11A CD70 DST HTR6 LEF1 PAFAH2 PTPRCAP TIA1
BCL2A1 CD93 EBI3 ICAM4 LILRA4 PAX3 PTX3 TIAF1
BDKRB1 CD99L2 EFEMP2 IER3 LILRA5 PAX5 PYCARD TIAM1
BLM CDC42 ELMO1 IFIT3 LY6G5B PDGFA RAC2 TLR10
BLNK CDKN1B EP300 IFNA21 LY75 PDGFRA RAG2 TLR6
BLR1 CDKN2A ERBB2 IFNGR2 LYN POU2AF1 RB1 TLR8
BMP4 CEACAM8 ERBB3 IGF1R MAP2K2 POU2F2 RFX5 TNC
BRAF CFHR2 ERBB4 IGJ MAP3K1 PPARGC1A RGS1 TNFAIP1
BRCA1 CFHR3 ETS1 IGSF2 MAP3K4 PRKRA S100A12 TNFRSF25
C1QL1 CFHR4 F5 IK MAPK13 PROM1 S100B TNIP1
C1QTNF2 CRISP3 FCN2 IL17RC MAPK8 PSCDBP SCARF1 TRAIP
C1QTNF3 CRLF1 FCRLA IL17RE MAPKAPK2 PSMA1 SECTM1 TRAT1
C1QTNF4 CSNK2A2 FOXN1 IL1F10 MCAM PSMA5 SET TREM1
C1QTNF6 CSNK2B FPR1 IL22RA1 MKNK1 PSMA6 SH2B2 TUBB
C1QTNF7 CTGF FPRL1 IL22RA2 MLLT6 PSMA7 SIGLEC1 TXNDC1
C3AR1 CTSH FTH1 IL31RA MMP9 PSMB2 SIGLEC9 UBD
CAMK2A CTSW FYB IRF4 MT2A PSMB3 SIVA1 YWHAG
CAMK2G CXCR6 GADD45B ISG15


Genes with Priority Score of 5


AATK BCL7C ELMO3 IFITM3 LRP5 NFATC4 PSMA3 SLC14A1
ABO BDKRB2 EMR1 IFNA10 LST1 NFKBIL1 PSMB1 SLPI
ACOX1 BIRC4 EPOR IFNA13 LTK NFKBIL2 PSMB4 SOCS5
ACVR1 BIRC5 ERMAP IFNA14 LY6D NINJ1 PSMD11 SRF
ACVRL1 BLK F11R IFNA16 LY6E NINJ2 PSMD5 TACR1
ADAMDEC1 BMP2 F2 IFNA17 LY6G6D NKG7 PSMD8 TAL2
ADORA1 BMP5 F2R IFNA5 LY6H NLRP1 PSMD9 TBXAS1
ADORA3 BMP7 F7 IFNA6 LYZ NLRP12 PSTPIP1 TCF4
ADRB2 BMPR1A F8 IFNA7 MADCAM1 NOD1 PTCRA TCL1A
AGER BTNL2 FANCC IFNB3 MAEA NODAL PTGFRN TEC
AHSG CASP14 FANCD2 IFNW1 MAP2K3 NOTCH2 PTGIR TGFBI
AIF1 CBFA2T3 FCAMR IGF1 MAP2K6 NR4A2 PTH THBD
AKT2 CCL4L2 FCN1 IGFBP3 MAP3K10 NRP2 PTPN1 THPO
ALB CD300A FGFR1 IGLL1 MAP3K12 PAFAH1B1 PTPN13 THRA
ALK CD300LB FGFR2 IGSF8 MAP3K14 PAK1 PTPRJ TIAL1
ALOX15 CD302 FGG INDO MAP3K2 PAX7 PVR TNFAIP2
ALOX5 CDH2 FKBP1A INPP5D MAP3K3 PBX1 PVRL2 TNFRSF11B
ALPL CDH23 FKBP2 INS MAP3K7IP1 PBX2 RAC1 TNFRSF12A
ANPEP CEACAM3 FKBP3 IRF6 MAP3K7IP2 PBX3 RALBP1 TNFRSF6B
ANXA1 CEBPA FKBP6 ISLR MAP3K8 PCID1 REL TNFSF13
ANXA11 CER1 FKBP8 ITCH MAPK10 PCNA RET TNFSF15
AOX1 CFTR FLT3 ITFG1 MAPK12 PDCD4 RFXANK TNFSF9
AQP9 CHL1 FLT3LG ITGA7 MAPKAPK5 PDCD7 RFXAP TNIP2
ARF6 CLC FPRL2 ITGB1BP1 MARCKS PDGFC RHBG TREM2
ART4 CLCF1 GATA2 ITGB4BP MCL1 PF4V1 RHCG TRIAD3
ATF1 CLEC4C GNB2L1 JAM2 MEF2C PGDS RIPK2 TSTA3
ATF4 CLEC4D GPR65 KCNQ1 MFI2 PGLYRP1 RIPK3 TXLNA
AXIN1 CMA1 GSK3B KDR MITF PGLYRP2 RPS6KA2 TYROBP
AZGP1 CMTM1 GYPE KIR2DS3 MKNK2 PIGR RPS6KA4 ULBP2
AZU1 CMTM6 HABP2 KLKB1 MLLT1 PIK3R1 RPS6KA5 ULBP3
BAG1 CMTM7 HAS1 KLRA1 MLLT3 PIK3R2 RUNX1 VWF
BAG3 COLEC12 HHEX KLRC3 MLLT4 PLA2G2A S100A9 WAS
BAK1 CRTAM HM13 KLRC4 MNDA PLA2G2D SART3 WASF1
BANK1 CTSK HMCN1 KLRG1 MS4A2 PLA2G4C SCARB2 WASF3
BAT1 CUL4A HMMR L1CAM MS4A3 PLA2G7 SCGB3A1 WIPF1
BAT3 CUTL1 HNF4A LAMB1 MS4A5 PLXNC1 SDF2 WNT3A
BAT4 DEFB118 HNMT LAMP2 MST1 PPARBP SDF2L1 WWP1
BAT5 DGKD HRH1 LBP MUC1 PRDX2 SEMA3A XG
BCAR1 DLG1 HSPA1A LEP MUC5AC PRKACA SERPINA3 XK
BCL10 DOCK1 HSPA1B LGALS3 MUC5B PRKCB1 SIGLEC11 XRCC6
BCL11B EDA ICAM5 LGALS3BP MXI1 PRKRIR SIGLEC7 YARS
BCL2L1 EGR1 IFI30 LGALS4 MYOD1 PROC SIGLEC8 YWHAH
BCL2L10 EIF2AK2 IFI44 LGALS8 NBN PRTN3 SIRPA YWHAQ
BCL2L2 ELK1 IFIH1 LIFR NCKAP1 PSEN1 SIRT1 YWHAZ
BCL7A ELK4 IFIT5 LILRA6 NCOA6 PSMA2 SLA2 YY1
BCL7B ELMO2 IFITM2


Genes with Priority Score of 4


CCL3L3 CD200R2 CD300C DEFB104A DEFB127 IL31 TGFBR2 TICAM2
CCL4L1 CD248 CD300LG DEFB125 DEFB129 SLAMF8 TGFBR3 ZFP36
CD164L2 CD2BP2 CD33L3 DEFB126 HAX1 TGFB3 TICAM1