Intracellular signaling pathway ; GO:0023034

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12/4/10

Redefined intracellular signaling pathway ; GO:0023034 from:
The series of molecular events whereby information is sent from one location to another within a living organism.
to:
The series of molecular events whereby information is sent from one location to another within a cell.

Removed the following cell-surface receptor signaling pathway terms from intracellular signaling pathway ; GO:0023034:

glutamate signaling pathway ; GO:0007215
immune response-regulating cell surface receptor signaling pathway ; GO:0002768
integrin-mediated signaling pathway ; GO:0007229
lipopolysaccharide-mediated signaling pathway ; GO:0031663
pattern recognition receptor signaling pathway ; GO:0002221
toll-like receptor signaling pathway ; GO:0002224
smoothened signaling pathway ; GO:0007224
Toll signaling pathway ; GO:0008063
Wnt receptor signaling pathway ; GO:0016055
enzyme linked receptor protein signaling pathway ; GO:0007167
nuclear translocation of MAPK involved in osmosensory signaling pathway ; GO:0000208 (redundant parentage)
inactivation of MAPK activity involved in osmosensory signaling pathway ; GO:0000173 (redundant parentage)

Removed the following from both GO:0023034 and cell surface receptor linked signaling pathway ; GO:0007166

osmosensory signaling pathway ; GO:0007231

Made the following direct children of intracellular signaling pathway ; GO:0023034:

intracellular vesicle pattern recognition receptor signaling pathway ; GO:0002754
cytoplasmic pattern recognition receptor signaling pathway ; GO:0002753

Moved luteinizing hormone signaling pathway ; GO:0042700 under G-protein coupled receptor protein signaling pathway ; GO:0007186.

Moved the following to be a parent of cell surface receptor linked signaling pathway ; GO:0007166

CD40 signaling pathway ; GO:0023035
cytokine-mediated signaling pathway ; GO:0019221
peptidoglycan recognition protein signaling pathway ; GO:0061057



19/4/10

Merged intracellular signaling cascade ; GO:0007242 and signal transmission via intracellular cascade ; GO:0023013 into intracellular signaling pathway ; GO:0023034. Cleared up redundant parentage and removed parentage of merged terms so that for now all the x pathway terms are only in the signaling pathway section, and not in the signal process section.

Gave intracellular receptor mediated signaling pathway ; GO:0030522 the following children:

  • blue light signaling pathway ; GO:0009785

Renamed protein kinase cascade ; GO:0007243 to intracellular protein kinase cascade ; GO:0007243:

A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. to: A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

Also renamed the regulation terms

Gave GO:0007243 the additional parent signal transmission via phosphorylation event ; GO:0023014.