Ontology meeting 2017-07-21
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Conference Line
Agenda
Discussion:
How will we distribute ontology editing tasks for the signaling work? Shall an editor join each group. Kimberly and DavidH can't do it all.
https://github.com/geneontology/go-ontology/projects/1
August Meeting Agenda
- Will be added to the logistics page
Minutes
- On call: Chris, David H., Eric, Jim, Karen, Kimberly, Pascale, Tanya
Signaling Pathways
- Distributing ontology editing tasks
- Ca2+ Signaling - ?
- Annotation possibly claimed by Penelope?
- GPCR - Pascale
- No one has formally claimed the annotation part of this, yet
- MAPK - David H.
- Wnt - Kimberly (with Giulia and Helen)
- Ca2+ Signaling - ?
- Review of github organization for this project
Import Pipeline
- Chris has taken care of this
Vitamins vs Co-Factors
- Will need to work with ChEBI to request appropriate role curation
- Curators who filed the go-ontology ticket should work with ChEBI to get roles they need
- What will ontology editors then need to do?
- Right now, manual maintenance is required, i.e. manually decide what chemical roles get added
- Discuss this at the August meeting
Autophagy and CVT Pathway
- These two processes share some gene products
- CVT pathway relation to autophagy in the ontology has been examined several times in the past
- What's the correct relation?
- Molecular definitions of autophagy and related processes.
- How about grouping terms like autophagy-like process or autophagic machinery-dependent process?
- Curators should know what more specific process is being studied in the papers they're reading and use the more specific terms for annotations
- David H will add proposals for re-naming the grouping term in the corresponding ticket
GO Inferences Report
- Chris has fixed this
GO Slims
- We need someone to own each of the GO slims
- Set up a yaml metadata file for each GO slim
- Would include who is responsible for it
- Also document what the GO slim is used for
- Document practice for how each GO slim is generated
- Groups may be balancing, differently, number of terms in slim vs how many gps map to nothing
- Maybe periodically find list of genes that map to nothing and create a new grouping term in the ontology or not in the ontology, but useful for categorization?