Part of relation

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Overview and Scope of Use

  • 'part of' is used in several different contexts in GO annotations.

Relating Processes (MF to BP and BP to BP)

  • 'part of' is used to link MF to BP when:
    • the MF is an integral step in the process, i.e. it is either the first, last, or intervening MF in a process
  • 'part of' is used to link BP to BP when:
    • one process is a subprocess of a larger process, e.g. cytokinesis is 'part of' mitotic cell cycle

Relating Anatomical Entities

  • 'part of' is used to link anatomical entities when:
    • one anatomical entity is fully contained within another anatomical entity, e.g. nucleus is 'part of' hepatocyte

Relating Gene Products to Protein-containing Complexes

  • 'part of' is used to link gene products to protein-containing complexes when:
    • the gene product is an integral component of the protein-containing complex

Annotation Usage Guidelines

GO-CAM Modeling

  • What to capture:
    • In GO-CAM modeling, 'part of' is used to link:
      • Molecular Function to Biological Process
      • Biological Process to Biological Process
      • Anatomical Entity to Anatomical Entity (note that Anatomical Entity includes GO Cellular Component)

Gene Product to Term

  • What to capture:
    • In standard GO annotation, 'part of' is used to link:
      • Genes or gene products to protein-containing complexes (GO:0032991 or children)
  • What not to capture:
    • To annotate gene products to cellular anatomical entities or virion components, use 'located in' or 'is active in', not 'part of'.

Annotation Extensions

  • What to capture:
    • In annotation extensions, like GO-CAM modeling, 'part of' is used to link:
      • Molecular Function to Biological Process
      • Biological Process to Biological Process
      • Anatomical Entity to Anatomical Entity (note that Anatomical Entity includes GO Cellular Component)


Ontology Usage Guidelines

  • In the ontology, 'part of' is used to link:
    • Molecular Function to Biological Process
    • Biological Process to Biological Process
    • Cellular Component to Cellular Component

Examples

Relations Ontology

part of

Review Status

Last reviewed: March 2, 2023 Reviewed by: Pascale Gaudet, David Hill, Kimberly Van Auken

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