Protein kinase C signaling cascade ; GO:0070528

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PKC is a a family of Serine/Threonine kinases

ACTIVATION OF PKC

• Activated by Ca++ or DAG (e.g. downstream of GPCRs)

DOWNSTREAM TARGETS OF PKC

• PKC phosphorylates a range of downstream targets; it's effects are very cell-type specific.

QUESTIONS

Where does PKC signaling start and end? Does it include anything that goes THROUGH PKC, or does it START with PKC activity?

References

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