Response to x annotation guidelines

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The definition of the top-level 'response to' terms has been updated to indicate where the response begins and ends: Any process that results in a change in state or activity of a cell or organism as the result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. This change was made and released in ontology version 1.1960

  • Examples:
    • response to stimulus ; GO:0050896 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism
    • GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. Advisory quality control check: High level 'response to' terms should not directly be used for annotation, unless additional information is supplied in column 16. Be careful to use IEP when the experiment is observing expression level. Example: PMID:8888624 and annotation for A. thaliana BIP1. Should use IEP than IDA.


See also Annotation_consistency:_'Response_to'_terms