2011 UCL Meeting Agenda: Difference between revisions

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** Column 16 usage and development by groups
** Column 16 usage and development by groups
*** Examples of how existing ontology terms will be replaced by annotation extension using column 16 (E.g. structural molecule activity, response element binding).


* Annotation Proposals and Discussions
* Annotation Proposals and Discussions

Revision as of 10:38, 12 October 2011

back to meeting logistics page

Agenda

Coffee from 9.00am

Morning session to start at 9:30am

End of sessions: 6pm Monday and Tuesday, 2pm on Wednesday

On Wed morning, several of us intend to meet with the CHEBI group who are going to come over to UCL. We were thinking perhaps we do the meeting wrap-up first thing on the Wed morning - action items, next meeting date etc. and then we can meet with CHEBI immediately afterwards. We thought perhaps another smaller group meeting might run in parallel (annotation-based?). Ruth is looking into booking additional rooms. [Jane]

GOC dinner Monday 6:30pm: Sardo 47 Grafton Way http://www.sardo-restaurant.com/index.html

Software

Milestones Report

  • Overview of software group activities and Roadmap ~~ Chris
    • New architecture
  • AmiGO 2 alpha ~~ Seth
    • amigo2 walkthrough demo
    • Example queries using c16
      • CL examples (mouse annotations)
      • POMBE examples
      • Treatment of evidence types
    • overview of architecture, use of Solr. Demo of Solr API
    • opportunities for integration with QuickGO ~~ Tony, Chris
  • GOLD beta
    • GAF services
      • Annotation file QC
      • Inference of new annotations
        • Use of logical definitions to suggest deeper annotations
        • Cross-ontology inference using part_of and occurs_in
    • Loading of phylogenetic data ~~ Sven
  • OBO-Edit ~~ Heiko/Chris
    • 2.1 Release
    • 2.2 Plans : mostly maintenance, a few key features, integration of obo2owl code
    • Beyond 2.2. - should there be a 3.0? Proteg4 plugin? Web-based tool? Lego?
  • TermGenie 1 beta ~~ Heiko
    • Retiring TG0
    • Extensions - additional templates
    • Integration with ontology roadmap
    • Use of TG as SF replacement ("freeform" term creation)
  • obo2owl roundtripping ~~ Heiko
    • OORT
  • GPAD specification and tools ~~ Amelia
  • GO Galaxy ~~ Amelia
  • LEGO_Model_Draft_Specification ~~ Amelia, Chris, PaulT
  • PAINT report ~~ Suzi, PaulT

Ontology

  • Roadmap reporting ?
  • Ontology editing workflow ~~ Chris
    • Dual mode Obo-Edit and Protege editing
    • Introduction to fast OWL reasoners, what they can do for the ontology group
    • MIREOTing subsets of external ontologies into editors version
    • Using OORT to produce releases
    • Report on how the GO editors are using SourceForge: triage, jamborees etc ~~ Jane
    • Greater use of ontology constraints (disjointness, taxonomic constraints)
  • Update on cell ontology ~~ Chris (NB: would be good to do this by email before the meeting, to get an update on CL funding and workflow).
    • Integration with Uberon
    • Use in FANTOM5
    • Neuro-cell work
  • Update on signaling ~~ Rebecca
  • Update on viruses ~~ Jane
  • Update on transcription ~~ David (please make this a late time slot so Karen can call in: 3pm UK time at the earliest)
  • Update on GOCHE: ~~ David
  • Update on GO apoptosis project (Paola and Pablo)
  • Proposal to introduce new disjointness axioms into GO CC ~~ Chris
  • Ontology Release Files Proposal ~~ Chris
  • Relations
    • Update on RO and BFO ~~ Chris
    • GO subset of RO
    • Coordinating between annotation group and ontology group on GO subset of new RO
  • Cross-products
    • Short update on where the GO cross-products are up to: involved in, biosynthesis etc. ~~ Jane

Annotation Working Group (Emily, Rama)

  • Progress Report
    • Development of GO annotation guidelines. (Geneva and Transcription factors).
    • Progress on the Community Annotation Tool (PomBase) See wiki
    • ECO codes for GO annotation. See wiki
    • Annotation QCs, including taxon constraints.
    • Column 16 usage and development by groups
      • Examples of how existing ontology terms will be replaced by annotation extension using column 16 (E.g. structural molecule activity, response element binding).
  • Annotation Proposals and Discussions
    • IMEX Consortium's work on representing protein-protein interaction data: presentation by Sandra Orchard, IntAct, EBI, Cambridge UK (25 mins)
      • The annotation of the stoichiometry of binding by GO groups. Under the spotlight: protein homodimerization, protein tetramerization etc.
      • Annotation to Protein Complex objects: a suggested annotation format. see wiki page.
      • Use of the new relationship Ontology to describe relationships between entities in an annotation, and for the generation of detailed, composite GO terms
        • specific use for column 16 (annotation extension field
        • specific use proposed for explicitly defining a gp to GO term relationship. see wiki

Software Group: Annotation Display and Support activities?

  • presentation on the new GAF uploader tool? Supply of hard, soft and inferred annotations to submitters?
  • presentation on AmiGO2 and column 16 display intentions?

General Discussions

- Discussion on appropriate software tools to help manage and report progress on individual project milestones