21 SEPT 2010 RefGen Priorities Discussion (Archived)
Jump to navigation
Jump to search
Strategy to achieve broad coverage of genomes annotation
A. Systematic Curation of all PANTHER families
Strategies to prioritize
- Annotate all families where there is no annotations or just ND's (automatic?)
- Annotate all families already 'done' by MODs (431 families done until the lung project)
B. Curation by biological domain
Strategies to prioritize
See document from Emily and Pascale - Nov-Dec 2009 : GO textbook approach for annotation
C. Goal
- Paul: Suggestion : have some extra resources between now and December to do more tree curation.
- Kara: Mike could try 'fast pass' all next week, and get a better estimate as to how much time he needs to do it at a 'production' pace.
- Paul: do only cellular processes: see OBO file in PantherDB
Discussion and suggestions:
- Mike C: goals for the next 2 months have different impact from goals for the rest of the funding period
- Paul: We should generate stats for the grant to show proof of principle for the grant
- Factors to consider:
- How much EXP data we we have to work with ? The 431 families have more EXP data to work from
- Fast pass versus comprehensive annotation of trees?
- Kara: what if we only did BP and not MF?
- Factors to consider: