AmiGO Manual: Overview
Introduction
AmiGO is the official web-based set tools for searching and browsing the Gene Ontology database, which consists of a controlled vocabulary of terms covering biological concepts, and a large number of genes or gene products whose attributes have been annotated using GO terms.
It can be accessed online at the main installation or deployed locally.
To learn more about what the Gene Ontology is and what it does, please read the introductory documentation.
What can I do using AmiGO?
- search for a gene or gene product, or a list of gene or gene products, and view the GO term associations
- perform a sequence identity BLAST search and view the GO term associations for the genes or proteins returned
- search for GO terms and view the genes or gene products they are annotated to
- browse the GO ontology and view terms
- the slimmer tool can be used to map the granular annotations of the query set of genes to one or more high-level
- term enrichment: TODO
- GOOSE is for advanced users who want to run custom SQL queries against the GO database.
Availability
AmiGO is an open source software project and can be downloaded and installed as part of the go-dev CVS repository from the Gene Ontology SourceForge.net page.
For full installation instructions, please see the installation wiki pages.
Browser Compatibility
AmiGO is compatible with most modern operating system/browser combinations with good CSS support, including:
- Firefox on Linux, Windows, and Mac OS X.
- Mozilla/Netscape 6 on Linux, Windows, and Mac OS X.
- IE on Windows, but NOT on Mac OS X. IE on Mac OS X does support CSS standards.
- Safari on Mac OS X.
- Konqueror on Linux.
- Opera on Linux, Windows, and Mac OS X.
In order to use all of the functionality available in this version of AmiGO, we recommend that cookies are allowed and JavaScript is turned on. The Main Window
The HTML page you view may vary slightly in details.
Components
AmiGO is made up of several interacting programs that work together to create a coherent whole.
Main components
The most used components
AmiGO's major components are the ones that are listed at the top of every page; these are the ones where your work will usually begin.
Pages from the main components
Other Components
AmiGO's other components are those that have specialized output in result of some kind of action.
Versions
The current stable version is 1.5 (1.5.4.0, tagged amigo_1_5_4_0). It is available for direct download at SourceForge.net .
Information on the upcoming version is at the 1.6 site. There is also an article and link to the current beta site.
Version numbers are as follows:
A.B.C.D
A = Major release B = Standard release (general testing) C = Bugfix release (test of fixes) D = Text fix release (minor changes that don't need testing)
The last two numbers are mostly for internal use.
Articles
Application note in Bioinformatics.