Annotation Call August 12, 2014

Agenda

Phase terms in biological process

As Jane explained last time, the ontology editors have introduced biological phase (GO:44848) as a new term in the Process ontology to represent distinct periods when processes occur. These terms do not have relationship (is_a) to any other process terms and they all also have a do_no_annotate tag. happens_during should be used to connect other processes and these phase terms. Should curators use the phase term in col-16 with happens_during or precompose a term such as DNA replication during S-phase?

New relationship for col-16

There is a new relationship for annotation extensions, causally_upstream_of.

This is intended to be used to capture processes or functions that are upstream of the process or function in the primary annotation and are required for that downstream process/function to occur.

This cannot be represented by new GO terms because the first process/function is upstream of, rather than part of, the second process/function.

The documentation for this relation, including some examples of its use, is in the wiki page; http://wiki.geneontology.org/index.php/Annotation_Extension_Relation:causally_upstream_of