Annotation Conf. Call, July 28, 2015: Difference between revisions

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(Created page with "Category: Annotation Working Group ==Agenda== ==Overview by ontology editors== Why certain relations were going to be obsoleted ===Example papers===")
 
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===Example papers===
===Example papers===
Obsoleted relationship:
independent_of
PMID:25215947
Typically mitophagy is dependent on PARK2 / parkin (Uniprot O60260). However, in PMID:25215947, authors show that AMBRA1 (Q9C0C7)  (in presence of chemical inducers of mitochondrial depolarisation such as FCCP) initiates mitophagy independent of PARK2 / parkin.
What to do now that independent_of relation is obsoleted? Simplest to create new term instead? e.g. “parkin-independent mitophagy in response to mitochondrial depolarization”.

Revision as of 10:30, 21 July 2015


Agenda

Overview by ontology editors

Why certain relations were going to be obsoleted

Example papers

Obsoleted relationship: independent_of PMID:25215947 Typically mitophagy is dependent on PARK2 / parkin (Uniprot O60260). However, in PMID:25215947, authors show that AMBRA1 (Q9C0C7) (in presence of chemical inducers of mitochondrial depolarisation such as FCCP) initiates mitophagy independent of PARK2 / parkin. What to do now that independent_of relation is obsoleted? Simplest to create new term instead? e.g. “parkin-independent mitophagy in response to mitochondrial depolarization”.