Annotation Conf. Call, June 24, 2014: Difference between revisions

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==Curation consistency exercise==
==Curation consistency exercise==
===Col-16 Relationships that were obsoleted===
===Enzyme Regulator activity vs positive regulation of X terms===
===Enzyme Regulator activity vs positive regulation of X terms===



Revision as of 19:35, 18 June 2014

Agenda

Curation consistency exercise

Col-16 Relationships that were obsoleted

Enzyme Regulator activity vs positive regulation of X terms

In this paper authors show (text around Fig 3) that yeast POL30 (PCNA) stimulates the activity of yeast Apn2 (exonuclease activity).

In this paper the authors show that Aha1 stimulates the ATPase activity of Hsp90 (text around Figure 7). Aha1 name description is Activator of Hsp90 Atpase.

Both papers show similar data for enzyme activation. In the first case the authors don't call PCNA as enzymne activator, while Aha1 is named as an activator of Hsp90. How would you choose between the MF enzyme regulator term and an equivalent BP regulation term.

Expression paper (Judy/David)

http://dx.doi.org/10.1126/science.1246980