Annotation Conf. Call 2017-02-14: Difference between revisions
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*****involved_in_positive_regulation_of | *****involved_in_positive_regulation_of | ||
*For discussion: | *For discussion: | ||
*Use of 'within' vs 'involved_in' | **Use of 'within' vs 'involved_in' | ||
**Definitions | |||
***Formal definitions exist, but curators would like guidance on how experimental results inform selection of a given relation | |||
== Jenkins Jobs == | == Jenkins Jobs == |
Revision as of 12:06, 13 February 2017
Bluejeans URL
Agenda
Meeting Reminder
- Next Consortium Meeting: June 1-3, 2017 in Corvallis, Oregon
- Noctua Workshop on June 4th
- Reactome Workshop on June 5th
Qualifiers and Relations in GO
- Qualifiers are used in GAF and GPAD
- Modify the meaning of the association between a gene/gene product and GO term
- colocalizes_with
- contributes_to
- NOT
- Documentation on Qualifier Use
- Relations are used in GPAD, Annotation Extensions, and LEGO models
- In GPAD, the explicit relations between a gene/gene product and GO terms are ontology-specific:
- involved_in a BP
- enables a MF
- part_of a CC
- Annotation extension relations 'extend' the meaning of the GO term, providing additional biological context
- In LEGO models, relations describe the context in which activities (GO MFs) occur and how activities relate to one another
- In GPAD, the explicit relations between a gene/gene product and GO terms are ontology-specific:
New Relations for Modifying a Gene's Role in a Biological Process
- This issue is about adding more relations to the list that curators currently use to describe the relationship between a gene/gene product and a BP GO term.
- We have talked about doing something like this for a long time, with the overall goal being a more accurate representation of biology.
- The current proposal is to add:
- acts_upstream_of_or_within
- acts_upstream_of
- involved_in_regulation_of
- involved_in_or_involved_in_regulation_of
- involved_in
- involved_in_regulation_of
- involved_in_negative_regulation_of
- involved_in_positive_regulation_of
- acts_upstream_of
- acts_upstream_of_or_within
- For discussion:
- Use of 'within' vs 'involved_in'
- Definitions
- Formal definitions exist, but curators would like guidance on how experimental results inform selection of a given relation
Jenkins Jobs
February 28th Call
- Discussion of LEGO Models
- Sabrina (ZFIN)
- Midori (PomBase)