Annotation Conf. Call 2017-03-14

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Revision as of 11:08, 13 March 2017 by Vanaukenk (talk | contribs) (Working Groups)

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Bluejeans URL

https://bluejeans.com/993661940

Agenda

GO Meeting Reminder

Software, Infrastructure

  • GO-Help, Ontology migration to github, Jenkins pipeline - Chris, Seth, Moni
  • Migration of annotation files to github at some point in the future?

Annotation Review

  • Review of IMP annotations for possible use of new qualifiers
    • What is the scope of the issue? Are there general principles we can derive to help with applying new qualifiers to legacy annotations?
    • BP_Annotation_Qualifiers_Spreadsheet
    • Explore effects on enrichment analyses
    • David H has run gene sets from three papers using VLAD including and excluding IMP evidence codes.
  • Single-step biological processes - review annotations to help assess impact if such terms are obsoleted
    • Github ticket 'Remove all single-step BP classes'
    • What terms could possibly be considered single-step processes?
      • Look at MF-BP links
    • Mary D's analysis shows that there are 2380 bioentities that have experimental annotation to phosphorylation or its children that do not have annotation to kinase or its children. This is just one example.

Working Groups

  • Transcription factor decision tree
    • From Rachael: The update is that we have revised the decision tree, which is attached above (see github ticket), and we would like feedback on it from this working group. When the working group are happy with it, then we will announce it at a future annotation call and get it added to the website.
  • Annotating high throughput experiments