Annotation Conf. Call 2017-09-12

Meeting URL

• https://stanford.zoom.us/j/976175422

Agenda

Update on Signaling Projects

github/go-annotation Signaling Projects page

• JAK/STAT
• GPCR
• MAPK - David, Sabrina
• Wnt - Helen (Kimberly away)
  • receptor ligand activity #14120 https://github.com/geneontology/go-ontology/issues/14120
    • receptor agonist activity (GO:0048018) re-named 'receptor ligand activity' and new definition (http://amigo.geneontology.org/amigo/term/GO:0048018). Also removed relationships to ‘signal transduction' & 'receptor activator activity'
    • Kimberly has checked usage of receptor agonist activity in curation corresponds to ligand as defined above and looking at documenting criteria for using this term.
  • Review of 'receptor activator activity'
    • Inconsistent use. ~20 experimental annotations https://docs.google.com/spreadsheets/d/15HcC6LFgOhA-BdQHvKMRjk3e-uIaGvitD5xH8Qzdkpk/edit#gid=233101787, different activities/processes have been annotated with this term. (make ticket)
  • Review annotations of beta-catenin to DNA binding terms (make ticket)
  • Tickets: for merging ‘frizzled-2 binding’ with ‘frizzled binding’ https://github.com/geneontology/go-ontology/issues/14182, and moving 'smoothened binding' from under 'frizzled binding' https://github.com/geneontology/go-ontology/issues/14182.
  • Collecting publications for documentation to illustrate term use and assays https://docs.google.com/document/d/1S6pjVaSpqwDHB3Q-2JBf35BrgOD-Z9z3w8WjijWvjw8/edit
• Ca2+ (Penelope away)

Cambridge GO Meeting

• Review Meeting Agenda

Minutes

• On call: