Annotation Conf. Call 2017-10-24: Difference between revisions

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== Ontology Updates ==
== Ontology Updates ==
* [https://github.com/geneontology/go-ontology/projects/7 Transcription factor activity refactor]
*Pascale:
* Molecular Function terms describing 'transcription factors' - Pascale
** [https://github.com/geneontology/go-ontology/projects/7 Transcription factor activity refactor]
* See: [https://github.com/geneontology/go-ontology/issues/13588 Make parent term for transcription factor activity]
** Molecular Function terms describing 'transcription factors'  
** See: [https://github.com/geneontology/go-ontology/issues/13588 Make parent term for transcription factor activity]
** See: [https://github.com/geneontology/go-annotation/issues/1668 Transcription factor branch refactoring: overview of annotations of TFIIIC and TFIIB complexes]


== GOC Meetings Cambridge ==
== GOC Meetings Cambridge ==

Revision as of 13:51, 23 October 2017

Meeting URL

Agenda

Annotation QC

  • Manual annotation to uninformative high-level terms is strongly discouraged
    • See: improving specificity by banning high level terms #1648
    • For example: direct annotation to 'transport' (GO:0006810) is one case where a more specific annotation can likely be made
    • In AmiGO, there are 53 experimentally supported annotations to 'transport'.
    • Can groups check these annotations to see if a more granular term is appropriate?
    • Annotations according to group:
 (8) EcoCyc
 (7) EcoliWiki
 (7) MGI
 (7) PseudoCAP
 (6) SGD
 (5) UniProt
 (4) BHF-UCL
 (3) RGD
 (3) TAIR
 (2) GR
 (1) SynGO
  • PomBase has a list of >1300 high-level terms that have a 'do not manually annotate' flag
  • The proposal is to work through this list so annotations are consistent amongst all GOC members

Ontology Updates

GOC Meetings Cambridge

  • Review key action items from signaling workshop and GOC meeting
    • Focus on annotation to signaling pathways
    • Adoption of expanded set of BP relations
    • Review use of contributes_to and colocalizes_with
    • Noctua into full production mode

Minutes

  • On call:
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