Annotation Conf. Call 2017-10-24: Difference between revisions
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** Review use of contributes_to and colocalizes_with | ** Review use of contributes_to and colocalizes_with | ||
** Noctua into full production mode | ** Noctua into full production mode | ||
** Representation of protein complexes, and their constituent members, in GO | ** Representation of protein complexes, and their constituent members, in GO and GO-CAM models | ||
*** [https://github.com/geneontology/go-annotation/issues/1662 inferring MFs from annotations to complex portal IDs to individual complex participants] | |||
***[https://github.com/geneontology/go-annotation/issues/1661 Protein complex representation in Noctua] | |||
= Minutes = | = Minutes = |
Revision as of 14:08, 23 October 2017
Meeting URL
Agenda
Annotation QC
- Manual annotation to uninformative high-level terms is strongly discouraged
- See: improving specificity by banning high level terms #1648
- For example: direct annotation to 'transport' (GO:0006810) is one case where a more specific annotation can likely be made
- In AmiGO, there are 53 experimentally supported annotations to 'transport'.
- Can groups check these annotations to see if a more granular term is appropriate?
- Annotations according to group:
(8) EcoCyc (7) EcoliWiki (7) MGI (7) PseudoCAP (6) SGD (5) UniProt (4) BHF-UCL (3) RGD (3) TAIR (2) GR (1) SynGO
- PomBase has a list of >1300 high-level terms that have a 'do not manually annotate' flag
- The proposal is to work through this list so annotations are consistent amongst all GOC members
Ontology Updates
- Pascale:
- Transcription factor activity refactor
- Molecular Function terms describing 'transcription factors'
- See: Make parent term for transcription factor activity
- See: Transcription factor branch refactoring: overview of annotations of TFIIIC and TFIIB complexes
GOC Meetings Cambridge
- Review key action items from signaling workshop and GOC meeting
- Focus on annotation to signaling pathways
- Adoption of expanded set of BP relations
- Review use of contributes_to and colocalizes_with
- Noctua into full production mode
- Representation of protein complexes, and their constituent members, in GO and GO-CAM models
Minutes
- On call: