Annotation Conf. Call 2017-10-24: Difference between revisions

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** Focus on annotation to signaling pathways
** Focus on annotation to signaling pathways
*** [https://drive.google.com/drive/u/0/folders/0B7bEr6HANSlGQmlCYm5VRHNMNW8 Folder on Google drive for signaling pathways working group]
*** [https://drive.google.com/drive/u/0/folders/0B7bEr6HANSlGQmlCYm5VRHNMNW8 Folder on Google drive for signaling pathways working group]
*** [https://docs.google.com/document/d/1wCzCkPL9ft20ZP5XnTn8IQAcxoFEduaBmzVWKN0hbU0/edit#heading=h.91lt0pk9qmy Signaling Workshop Meeting Minutes]
*** [https://docs.google.com/document/d/1wCzCkPL9ft20ZP5XnTn8IQAcxoFEduaBmzVWKN0hbU0/edit Signaling Workshop Meeting Minutes]
*** [https://github.com/geneontology/go-annotation/issues/1597 How to name specific MAPK pathways]
*** [https://github.com/geneontology/go-annotation/issues/1597 How to name specific MAPK pathways]
*** [https://github.com/geneontology/go-ontology/issues/14275 NTR: “receptor ligand agonist activity” and “receptor ligand antagonist activity”]
*** [https://github.com/geneontology/go-ontology/issues/14275 NTR: “receptor ligand agonist activity” and “receptor ligand antagonist activity”]

Revision as of 15:48, 23 October 2017

Meeting URL

Agenda

Annotation QC

  • Manual annotation to uninformative high-level terms is strongly discouraged
    • See: improving specificity by banning high level terms #1648
    • For example: direct annotation to 'transport' (GO:0006810) is one case where a more specific annotation can likely be made
    • In AmiGO, there are 53 experimentally supported annotations to 'transport'.
    • Can groups check these annotations to see if a more granular term is appropriate?
    • Annotations according to group:
 (8) EcoCyc
 (7) EcoliWiki
 (7) MGI
 (7) PseudoCAP
 (6) SGD
 (5) UniProt
 (4) BHF-UCL
 (3) RGD
 (3) TAIR
 (2) GR
 (1) SynGO
  • PomBase has a list of >1300 high-level terms that have a 'do not manually annotate' flag
  • The proposal is to work through this list so annotations are consistent amongst all GOC members

Ontology Updates

GOC Meetings Cambridge

Minutes

  • On call:
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