Meeting URL
Agenda
Annotation QC
- Manual annotation to uninformative high-level terms is strongly discouraged
- See: improving specificity by banning high level terms #1648
- For example: direct annotation to 'transport' (GO:0006810) is one case where a more specific annotation can likely be made
- In AmiGO, there are 53 experimentally supported annotations to 'transport'.
- Can groups check these annotations to see if a more granular term is appropriate?
- Annotations according to group:
(8) EcoCyc
(7) EcoliWiki
(7) MGI
(7) PseudoCAP
(6) SGD
(5) UniProt
(4) BHF-UCL
(3) RGD
(3) TAIR
(2) GR
(1) SynGO
- PomBase has a list of >1300 high-level terms that have a 'do not manually annotate' flag
- The proposal is to work through this list so annotations are consistent amongst all GOC members
Ontology Updates
GOC Meetings Cambridge
- Review key action items from signaling workshop and GOC meeting
- Focus on annotation to signaling pathways
- Adoption of expanded set of BP relations
- Review use of contributes_to and colocalizes_with
- Noctua into full production mode
- Meetings on second and fourth Wednesdays at 8am PST to discuss issues
- Representation of protein complexes, and their constituent members, in GO and GO-CAM models
- Review HTP annotations
Minutes