Annotation Conf. Call 2018-01-09: Difference between revisions
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*[https://github.com/geneontology/go-annotation/issues/1714 Review annotations to beta catenin] | *[https://github.com/geneontology/go-annotation/issues/1714 Review annotations to beta catenin] | ||
*[https://github.com/geneontology/go-annotation/issues/1696 PANTHER:PTN000139394: remove wnt binding annotation to smoothened receptors] | *[https://github.com/geneontology/go-annotation/issues/1696 PANTHER:PTN000139394: remove wnt binding annotation to smoothened receptors] | ||
*https://github.com/geneontology/go-ontology/issues/14275 | *https://github.com/geneontology/go-ontology/issues/14275 NTR: “receptor ligand agonist activity” and “receptor ligand antagonist activity”] | ||
==Requests for Proposals== | ==Requests for Proposals== |
Revision as of 11:30, 8 January 2018
Meeting URL
Agenda
Review of Cambridge meeting action items and milestones for 2018-05 GOC meeting in NYC
In geneontology/go-annotation on github, there is a Milestone '2018-05 GOC meeting'
Annotation Review
HTP Annotations
- Review HTP annotations
- Forward genetic screens - needs clarification
- HTP-types will not be allowed as evidence for ISS+ISO
Signaling Workshop
In geneontology/go-annotation on github, there is a label 'GO workshop signaling 2017'
General Signaling Issues
Ca2+ Signaling - Fertilization
GPCR-mediated cAMP Signaling
- Review annotations to 'cAMP biosynthetic process'
- Review annotation for GPCR
- NTR: regulation terms for adenylate cyclase-activating adrenergic receptor signaling pathway
- cAMP biosynthetic process - merges & obsoletion
JAK/STAT Signaling Pathway
MAPK Cascade
Canonical Wnt Signaling Pathway
- PAINT:PTN000226268 Wnt signaling pathway to positive regulation of...
- Review annotations to beta catenin
- PANTHER:PTN000139394: remove wnt binding annotation to smoothened receptors
- https://github.com/geneontology/go-ontology/issues/14275 NTR: “receptor ligand agonist activity” and “receptor ligand antagonist activity”]
Requests for Proposals
Protein Complexes Working Group
- Inferring MF annotations for complex members
- Proposal for guidelines for using contributes_to
- should we really use "colocalizes_with" with cc complex terms
- Protein complex representation in Noctua
- Do we have to hard-code CC complex terms to MF and BP relationships in the ontology?
- Working group established, one meeting in late November
- Next meeting?
Annotation Relations - Cellular Component
- should we really use "colocalizes_with" with cc complex terms
- Relations to describe gene product - component annotation
InterPro2GO Pipeline
- InterPro2GO pipeline
- Need to establish a working group here
Engaging External Experts
Requests for Guidelines
GO-CAM and Noctua
- QC for Noctua models
- New qualifiers for biological processes - including how to deal with legacy annotations
Minutes
- On call: