Acts on population of

Back to Annotation usage examples for each annotation extension relation

Definition

The relationship that links an entity with a process in which the process has more than one participant that is of the same entity type.

Child terms

None.

Scope of use

Domain

GO:0003674 (molecular_function) or GO:0008150 (biological_process)

Range

CL:0000000 (cell) or GO:0005575 (cellular component) or WBbt:0004017 (cell)

Annotation Extension Usage Examples

1. Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1:

Statement from paper:

Data obtained at 30 days posttransplantation showed that the CRA of Brca2Δ27/Δ27 BM cells was markedly below that corresponding to WT BM cells (Fig. 5B). Furthermore, CRA values from Brca2Δ27/Δ27 BM progressively dropped as the posttransplantation time was increased (Fig. 5B), indicating that, at least under the proliferative stress mediated by a BM transplantation, the repopulating function of Brca2Δ27/Δ27 HSCs is markedly impaired.

Gene Name (col 2)	GO ID (col 5)	Reference (col 6)	Evidence (col 7)	Annotation Extension (col 16)
O08665 Sema3a	GO:0008045 motor neuron axon guidance	PMID:18804103	IMP	acts_on_population of(CL:0005025 visceromotor neuron)

Using example (from above) to demonstrate Folding_and_Unfolding using the relationship acts_on_population_of

1. SEMA3A signals through NRP1 and PLXNA4 to guide the axons of facial visceromotor neurons:

Folded/unfolded	Gene Name (col 2)	GO ID (col 5)	Reference (col 6)	Evidence (col 7)	Annotation Extension (col 16)	Parent terms of new folded GO term
Unfolded	O08665 Sema3a	GO:0008045 motor neuron axon guidance	PMID:18804103	IMP	acts_on_population of(CL:0005025 visceromotor neuron)
Folded	O08665 Sema3a	New GO ID visceromotor neuron motor neuron axon guidance	PMID:18804103	IMP		is_a GO:0008045 motor neuron axon guidance