Happens during

Definition

Identifies a process during which a molecular function or biological process occurs

Comment

To link a physical entity to a process by duration, use exists_during.

Synonym

occurs_during (EXACT)

Child terms

• None.

Scope of use

Domain

BFO:0000007 ! process (Biological Process or Molecular Function)

Range

BFO:0000007 ! process (Biological Process or Molecular Function)

Annotation Extension Usage Examples

1. A process occurring during cell development

Statement from paper:

In most cell systems that have been examined, the primary signal transduction pathway for BMPs involves phosphorylation of Smad-1 [22]... To determine if BMP-5 initiates similar signaling events in sympathetic neurons, cultured sympathetic neurons grown in the absence of glial cells were treated with BMP-5 for 30 or 60 min then analyzed by Western blotting using Abs specific for total Smad-1 or for phosphorylated Smad-1. Phosphorylation of Smad-1 is evident within 30 min after exposure to BMP-5 (Figure 4A) with significantly increased pSmad-1 levels apparent at 60min. In contrast, treatment with BMP-5 did not alter levels of total Smad-1 (Figure 4B).

Gene Name (col 2)	GO ID (col 5)	Reference (col 6)	Evidence (col 7)	Annotation Extension (col 16)
P22003 BMP5	GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation	PMID:11580864	IDA	happens_during(GO:0016358 dendrite development)

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