Has output
Definition
- The molecule that is produced as a result of a molecular function or a biological process.
- Note that more than one output may be used for an annotation: this means that there are multiple products for a reaction. However if an enzyme acts 'different substrates which results in different products, this should be captured as an independent annotation (or an independent statement in Protein2GO).
- Formal definition in Relations Ontology (RO): RO:0002234 has output definition: P has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p.
Scope of use
Domain
Domain refers to the GO terms that can be further specified with the relation.
- BFO:0000007 process, which corresponds to GO Biological Process and Molecular Function
Range
Range describes the types of entities that can be used with the relation.
- Modified gene product, e.g. PRO identifier
- ChemicalEntity: CHEBI:24431 chemical entity
- ProteinContainingComplex: GO:0032991 protein-containing complex
Annotation Extension Usage Examples
1. Specifying the product of a catalytic activity
Human DGKA phosphorylates 1,2-diacyl-sn-glycerol, producing 1,2-diacyl-sn-glycerol 3-phosphate, PMID:22627129.
Annotation for DGKA | |
Gene product | UniProtKB:P23743 DGKA |
GP2term relation | enables |
GO term | GO:0004143 diacylglycerol kinase activity, has output(CHEBI:29089 1,2-diacyl-sn-glycerol 3-phosphate) |
Evidence | IDA |
Reference | PMID:22627129 |
Note that this reaction has both an input and an output:
Annotation for DGKA | |
Gene product | UniProtKB:P23743 DGKA |
GP2term relation | enables |
GO term | GO:0004143 diacylglycerol kinase activity, has input(CHEBI:17815 1,2-diacyl-sn-glycerol), has output(CHEBI:29089 1,2-diacyl-sn-glycerol 3-phosphate) |
Evidence | IDA |
Reference | PMID:22627129 |
Back to Annotation usage examples for each annotation extension relation