Has small molecular inhibitor: Difference between revisions
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!GO ID (Col 5) | !GO ID (Col 5) | ||
!Reference (Col 6) | !Reference (Col 6) | ||
!Evidence | |||
!Extension (Col 16) | !Extension (Col 16) | ||
!Parent terms for new folded GO term | !Parent terms for new folded GO term | ||
|- | |- | ||
| Unfolded | | Unfolded | ||
| | | P10869, <font color = "green">HOM3</font> | ||
| GO:0004072 <font color = "green">aspartate kinase activity</font> | |||
| PMID:18626862 | |||
| IDA | |||
|inhibited_by: CHEBI:16857<font color = "green">L-threonine </font> | |||
| | |||
|- | |||
| Folded | |||
| P10869, <font color = "green">HOM3</font> | |||
| ?? | |||
|PMID:18626862 | |||
|IDA | |||
| | | | ||
| | | | ||
|- | |- | ||
Revision as of 18:32, 26 February 2015
Back to Annotation usage examples for each annotation extension relation
Definition
Identifies a chemical substance that decreases the activity of the gene product.
Comment
This relation should not be used to annotate one gene product regulating another's activity; a regulator Molecular Function or regulation Biological Process should be used in such cases.
Synonyms
activity_decreased_by (EXACT)
inhibited_by_chemical (EXACT)
inhibited_by_substance (EXACT)
Child terms
- None.
Scope of use
Domain
GO:0003674 ! molecular_function
Range
CHEBI:24431 ! chemical entity
Annotation Extension Usage Examples
| Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | With (col 8) | Annotation Extension (col 16) |
|---|---|---|---|---|---|
| P10869, HOM3 | GO:0004072 aspartate kinase activity | PMID:18626862 | IDA | inhibited_by: CHEBI:16857L-threonine | |
| P32783, ABD1 | GO:0004482, mRNA (guanine-N7-)-methyltransferase activity | PMID: 7623811 | IDA | inhibited_by: CHEBI:16680 S-adenosyl-L-homocysteine |
Using examples to demonstrate Folding_and_Unfolding using the relationship inhibited_by
| Folded/unfolded | DB (Col 2) | Object (Col 3) | GO ID (Col 5) | Reference (Col 6) | Evidence | Extension (Col 16) | Parent terms for new folded GO term |
|---|---|---|---|---|---|---|---|
| Unfolded | P10869, HOM3 | GO:0004072 aspartate kinase activity | PMID:18626862 | IDA | inhibited_by: CHEBI:16857L-threonine | ||
| Folded | P10869, HOM3 | ?? | PMID:18626862 | IDA | |||
| Folded |
OWL class expression:
Back to Annotation usage examples for each annotation extension relation