Difference between revisions of "Annotation Extension Relation:inhibited by"

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(Using examples to demonstrate Folding_and_Unfolding using the relationship inhibited_by)
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'''OWL class expression:''' GO: 0004072 <font color = "red">aspartate kinase activity</font> is inhibited_by some CHEBI: 16857 <font color = "red">L-threonine </font>
 
'''OWL class expression:''' GO: 0004072 <font color = "red">aspartate kinase activity</font> is inhibited_by some CHEBI: 16857 <font color = "red">L-threonine </font>
  
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{| class="wikitable" border="1"
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! Folded/unfolded
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!Object (Col 2)
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!GO ID (Col 5)
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!Reference (Col 6)
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!Evidence
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!Extension (Col 16)
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!Parent terms for new folded GO term
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|-
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| Unfolded
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| P32783, <font color = "green">ABD1</font>
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| GO:0004482, <font color = "green">mRNA (guanine-N7-)-methyltransferase activity</font>
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| PMID: 7623811
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| IDA
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|inhibited_by: CHEBI:16680 <font color = "green">S-adenosyl-L-homocysteine</font>
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|
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|-
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| folded
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| P32783, <font color = "green">ABD1</font>
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|
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| PMID: 7623811
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| IDA
 +
|
 +
|
 +
|-
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|}
  
 
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Revision as of 14:42, 26 February 2015

Back to Annotation usage examples for each annotation extension relation

Definition

Identifies a chemical substance that decreases the activity of the gene product.

Comment

This relation should not be used to annotate one gene product regulating another's activity; a regulator Molecular Function or regulation Biological Process should be used in such cases.

Synonyms

activity_decreased_by (EXACT)

inhibited_by_chemical (EXACT)

inhibited_by_substance (EXACT)

Child terms

  • None.

Scope of use

Domain

GO:0003674 ! molecular_function

Range

CHEBI:24431 ! chemical entity

Annotation Extension Usage Examples

Gene Name (col 2) GO ID (col 5) Reference (col 6) Evidence (col 7) With (col 8) Annotation Extension (col 16)
P10869, HOM3 GO:0004072 aspartate kinase activity PMID:18626862 IDA inhibited_by: CHEBI:16857L-threonine
P32783, ABD1 GO:0004482, mRNA (guanine-N7-)-methyltransferase activity PMID: 7623811 IDA inhibited_by: CHEBI:16680 S-adenosyl-L-homocysteine

Using examples to demonstrate Folding_and_Unfolding using the relationship inhibited_by

Folded/unfolded Object (Col 2) GO ID (Col 5) Reference (Col 6) Evidence Extension (Col 16) Parent terms for new folded GO term
Unfolded P10869, HOM3 GO:0004072 aspartate kinase activity PMID:18626862 IDA inhibited_by: CHEBI:16857L-threonine
Folded P10869, HOM3  ?? PMID:18626862 IDA


OWL class expression: GO: 0004072 aspartate kinase activity is inhibited_by some CHEBI: 16857 L-threonine

Folded/unfolded Object (Col 2) GO ID (Col 5) Reference (Col 6) Evidence Extension (Col 16) Parent terms for new folded GO term
Unfolded P32783, ABD1 GO:0004482, mRNA (guanine-N7-)-methyltransferase activity PMID: 7623811 IDA inhibited_by: CHEBI:16680 S-adenosyl-L-homocysteine
folded P32783, ABD1 PMID: 7623811 IDA

Back to Annotation usage examples for each annotation extension relation