Part of - deprecated: Difference between revisions

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See http://obofoundry.org/ro#part_of


In GO (and in RO), A [[part_of]] B means that ''every'' A is [[part_of]] ''some'' B.
==Definition==
 
A [[part_of]] B means that ''every'' A is [[part_of]] ''some'' B.


For example: nucleus [[part_of]] cell
For example: nucleus [[part_of]] cell
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[[Category:Reasoning]]
[[Category:Reasoning]]


'''Annotation Examples:'''
 
==Annotation Examples==




== Enhancing Cell Component Annotations ==
=== Enhancing Cell Component Annotations ===


=== Localization ===
==== Localization ====


===Specifying that a gene product is located in a cellular component of a specific cell type===
====Specifying that a gene product is located in a cellular component of a specific cell type====


Examples of these usages of part_of can be found on the documentation page for [[Column_16:_Cell_Type]]
Examples of these usages of part_of can be found on the documentation page for [[Column_16:_Cell_Type]]


== Enhancing Molecular Function and Biological Process Annotations ==
=== Enhancing Molecular Function and Biological Process Annotations ===


=== Specifying the developmental stage at which a process occurs ===
==== Specifying the developmental stage at which a process occurs ====


We can use a developmental stage ontology and the [[part_of]] relation. part_of is used because both the process/function and the developmental stages are things with temporal parts (they are occurrents in bfo-speak).
We can use a developmental stage ontology and the [[part_of]] relation. part_of is used because both the process/function and the developmental stages are things with temporal parts (they are occurrents in bfo-speak).
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   col16: part_of(ZFS:0000023)
   col16: part_of(ZFS:0000023)


=== Functions carried out as part of a process ===
==== Functions carried out as part of a process ====


We use the [[part_of]] relation to link function and process (this relation is already used for the inter-ontology links)
We use the [[part_of]] relation to link function and process (this relation is already used for the inter-ontology links)
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This is harmless but pointless, because we know that kinase activity is part_of phosphorylation from gene_ontology_ext
This is harmless but pointless, because we know that kinase activity is part_of phosphorylation from gene_ontology_ext


== Function-Process-Component threesomes ==
=== Function-Process-Component threesomes ===


   col5: GO Function ID
   col5: GO Function ID

Revision as of 07:24, 3 May 2012

Definition

A part_of B means that every A is part_of some B.

For example: nucleus part_of cell

Contrast with has_part


Annotation Examples

Enhancing Cell Component Annotations

Localization

Specifying that a gene product is located in a cellular component of a specific cell type

Examples of these usages of part_of can be found on the documentation page for Column_16:_Cell_Type

Enhancing Molecular Function and Biological Process Annotations

Specifying the developmental stage at which a process occurs

We can use a developmental stage ontology and the part_of relation. part_of is used because both the process/function and the developmental stages are things with temporal parts (they are occurrents in bfo-speak).

For example, apoptosis during Segmentation:1-4 somites in zebrafish

 col5: GO:0006915
 col16: part_of(ZFS:0000023)

Functions carried out as part of a process

We use the part_of relation to link function and process (this relation is already used for the inter-ontology links)

For example, if a gene product is observed to have GTPase activity as a part of the nerve growth factor receptor signaling pathway, you would annotate:

 col5: GO:0003924
 col16: part_of(GO:0048011)

Note you should also include a separate annotation in which GO:0048011 is in col5, so that people who are not using col 16 will not be worse off than they are now. See guidelines.

Note that you would not say something like this:

 col5: GO:0016301
 col16: part_of(GO:0016310)
  • GO:0016301 - kinase activity
  • GO:0016310 - phosphorylation

This is harmless but pointless, because we know that kinase activity is part_of phosphorylation from gene_ontology_ext

Function-Process-Component threesomes

 col5: GO Function ID
 col16: part_of(GO PROCESS ID),occurs_in(GO CC ID)

Also include 2 redundant annotation lines