Annotation Extension Relation:requires direct regulator

Definition

Annotated gene product requires direct regulation by the gene product or complex identified in the extension. Includes cases where the annotated gene product is a catalytic subunit of a complex and requires a regulatory subunit for activity as well as cases where the regulator acts directly but interacts transiently.

Comment

The gene product in the extension should be annotated to a "regulator" Molecular Function (implying that it acts directly to regulate the annotated gene product activity)

Child terms

• None.

Scope of use

Domain

GO:0003674 ! molecular_function

Range

ENTITY_UNION:0000001 ! gene product or complex