Annotation Relations

Gene Product to GO Term Relations

Biological Process

acts upstream of or within

acts upstream of or within, positive effect

acts upstream of or within, negative effect

acts upstream of

acts upstream of, positive effect

acts upstream of, negative effect

involved in

Molecular Function

enables

contributes to

Cellular Component

part of (GP2Term)

is active in

colocalizes with

GO-CAM Relations

Molecular Function to Gene Product

enabled by

Molecular Function to Cellular Component

occurs in

Molecular Function to Molecular Function

directly provides input for

directly positively regulates

directly negatively regulates

Molecular Function to Biological Process

part of

causally upstream of or within, positive effect

causally upstream of or within, negative effect

causally upstream of, positive effect

causally upstream of negative effect

Molecular Function to Inputs and Outputs

has input

has output

Molecular Function to Temporal Phase

happens during

Biological Process to Molecular Function

causally upstream of, positive effect

causally upstream of negative effect

positively regulates

negatively regulates

Biological Process to Cellular Component

occurs in

Biological Process to Cell or Anatomy Term

occurs in

Biological Process to Temporal Phase

happens during

Biological Process to Inputs and Outputs

has input

has output

Annotation Extension Relations

• Annotation Extension Relations

Relations Tables (works in progress)

Gene Product-to-GO Term Relations
Molecular Function	enables
	contributes to (as complex member)
Biological Process	involved in
	acts upstream of or within
	acts upstream of or within, positive effect
	acts upstream of or within, negative effect
	acts upstream of
	acts upstream of, positive effect
	acts upstream of, negative effect
Cellular Component	is active in
	part of
	located in
	colocalizes with

GO-CAM Relations
Molecular Function
Molecular Function - Gene Product	enabled by	protein kinase activity enabled by PLK1
Molecular Function - Location	occurs in	protein kinase activity occurs in cytosol
Molecular Function - Input	has input	protein kinase activity has input MCM3
Molecular Function - Output	has output	protein kinase activity has output MCM3-2P
Molecular Function - Temporal Phase	happens during	protein kinase activity happens during G1 phase
Molecular Function - Molecular Function	directly positively regulates	protein kinase activity directly positively regulates ion transmembrane transporter activity
Molecular Function - Molecular Function	directly negatively regulates	protein kinase activity directly negatively regulates peroxidase activity
Molecular Function - Molecular Function	directly provides input for	peptidase activity directly provides input for receptor activity