View source for CDKN1B

[[Category:Immune genes]]
[[Immune Gene Page C|Return to Listing of Immune Related Genes Beginning with 'C']]

== '''Information and Links''' ==

<big>'''CDKN1B''' ''cyclin-dependent kinase inhibitor 1B (p27, Kip1)''</big>

'''Also known as:  '''Cdkn1b, CDKN4, KIP1, MEN1B, P27KIP1, p27, p27Kip1

<div align="right"><small>Nomenclature accurate as of April 27, 2007</small></div>

'''Gene Details:  '''[http://www.genenames.org/data/hgnc_data.php?hgnc_id=1785 HGNC] (human)   [http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:104565 MGI] (mouse)   [http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=69062 RGD] (rat)

'''Entrez Gene Pages:  '''[http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1027&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum Human]    [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12576&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum Mouse]    [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83571&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum Rat]    [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=512613&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum Cow]    


'''<u>Orthology Predictions</u>'''

Through [http://www.informatics.jax.org/searches/homology_report.cgi?id=MGI:104565 MGI] (human and other mammalian species)

Through [http://www.genenames.org/cgi-bin/hcop.pl?species_pair=Human+and+Any+species&column=symbol&query=CDKN1B&Search=Search HGNC/HCOP] (vertebrate and invertebrate orthologs)


== '''Existing GO Annotation''' ==

Use the links below as well as the links to the gene information pages above to check existing GO annotation for '''CDKN1B'''.
  
					GO annotation for a particular gene in a set of orthologous genes will vary between species depending upon the experimental evidence available, annotation completeness, and fundamental differences in biology.  
					Please take note of any aspects of the gene's biology that are not represented in the existing GO annotations.


'''Gene Ontology Consortium Amigo Browser:'''  [http://www.godatabase.org/cgi-bin/amigo/go.cgi?action=query&view=query&query=CDKN1B&search_constraint=gp Many Species]

'''GOA QuickGO Browser:  '''[http://www.ebi.ac.uk/ego/GSearch?query=P46527&mode=name_syno&ontology=all_ont Human]   [http://www.ebi.ac.uk/ego/GSearch?query=P46414&mode=name_syno&ontology=all_ont Mouse]   [http://www.ebi.ac.uk/ego/GSearch?query=O08769&mode=name_syno&ontology=all_ont Rat]   

'''MGI Browser:  '''[http://www.informatics.jax.org/javawi2/servlet/WIFetch?page=markerGO&id=MGI:104565 Mouse]   [http://www.informatics.jax.org/javawi2/servlet/WIFetch?page=GOOrthologyGraph&id=MGI:104565 Mouse-Human-Rat Comparative GO Graph]

'''RGD Browser:  '''[http://rgd.mcw.edu/tools/genes/gene_ont_view.cgi?id=69062 Rat]


== '''Community Input Section''' ==

Examine the GO annotations for '''CDKN1B''', using the links above, and tell us about aspects of its biology that are still unannotated by editing the wiki page directly.  
					GO curators are notified when particular gene pages are changed and will act upon your contributed information to create new GO annotations.

Supporting literature may be found through the GeneRIFs on the Entrez Gene pages above, or directly through [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed PubMed] or [http://www.ebi.ac.uk/citexplore/ CiteXplore]


'''Please duplicate and complete the following sections:'''

________________________________________________________

Gene function, process, cellular location or interacting partner (as a list or short summary):

Method or evidence used to support the annotation (eg enzyme assay, flow cytometry, immunoprecipitation, mutant phenotype, etc.):

Supporting Literature Reference (PubMedID or citation):

Contact email address (optional):

Additional notes:

________________________________________________________


'''<big>Thank you</big>'''


''<big>[[Example GO annotation submission|Link to example of submitted GO annotation]]</big>''


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