Database Objects: Difference between revisions

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Because a single gene may encode very different products with very different attributes, GO recommends associating GO terms with database objects representing gene products rather than genes. At present, however, many participating databases are unable to associate GO terms to gene products, and therefore use genes instead. If the database object is a gene, it is associated with all GO terms applicable to any of its products. See the annotation file format guide for more information.
Current database objects used in GO annotations include gene identifiers, protein identifiers and RNA identifiers. The type database object applied in an annotation is indicated in column 12 (for example: 'protein','gene_product','snRNA').
 
Because a single gene may encode a number of different products with different attributes, GO recommends using column 17, where possible, to indicate a particular gene product form (such as a protein identifier, protein isoform identifier).
If no further specificiation is possible in column 17 from the evidence available to the curator, then the Consortium suggests that the annotation object is associated with all GO terms applicable to any of its products. See the annotation file format guide for more information.

Revision as of 06:58, 15 June 2011

Current database objects used in GO annotations include gene identifiers, protein identifiers and RNA identifiers. The type database object applied in an annotation is indicated in column 12 (for example: 'protein','gene_product','snRNA').

Because a single gene may encode a number of different products with different attributes, GO recommends using column 17, where possible, to indicate a particular gene product form (such as a protein identifier, protein isoform identifier).

If no further specificiation is possible in column 17 from the evidence available to the curator, then the Consortium suggests that the annotation object is associated with all GO terms applicable to any of its products. See the annotation file format guide for more information.