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Revision as of 19:14, 24 December 2009 by Suzi (talk | contribs) (Presentations and Publications)

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EcoliWiki & GONUTS Operation:

James C. Hu

Daniel Renfro

Nathan Liles

Lance Ferguson

Amanda Supak


Debby Siegele

Brenley McIntosh

Adrienne Zweifel

Annotation Progress

Gene Products # of GPs with only IEA # of GPs with manual annotations (not IEA) # GPs with an annotation (IEA or other)
4482 1870 1625 3495

Methods and strategies for annotation

At EcoliWiki, we have prioritized the RefGenome genes for annotation first. These genes are listed on our Home Page after they are provided to us by the RefGenome group. We annotate the most recent genes first and work on previous genes whenever possible. Other genes not included in the RefGenome list are also annotated. When a gene product is annotated, we often contact the corresponding author to invite her/him to add/delete/change annotations based on their expertise from working directly with this gene product.

Presentations and Publications


Ontology Development Contributions

Debby and Jim have been contributing to ontology development and discussions on electron transport and binding terms. Brenley has been involved in the virus ontology term development.

Annotation Outreach and User Advocacy Efforts

EcoliWiki puts a list of the Reference Genome genes in E. coli on the EcoliWiki Home Page each month. EcoliWiki also emails recent authors and requests participation in GO annotation.

Other Highlights:


The Gene Ontology Normal Usage Tracking System (GONUTS) is a web-based resource for researchers using Gene Ontology (GO) terms and GO. It has expanded from focusing on documentation of GO terms to also become a valuable online database for organisms without their own MOD (model organism database), such as Gallus gallus .

2. CACAO (Community Assessment of Community Annotation with Ontologies)

We are developing an undergraduate annotation course using GO terminology and GONUTS to help students learn the annotation process and study bioinformatics.