Example GO annotation submission
From GO Public
IL1A interleukin 1, alpha
Also known as: Il1a, IL-1A, IL1, IL1-ALPHA, IL1F1, Il-1a
Through MGI (human and other mammalian species)
Through HGNC/HCOP (vertebrate and invertebrate orthologs)
Existing GO annotation
Use the links below as well as the links to the gene information pages above to check existing GO annotation for IL1A.
GO annotation for a particular gene in a set of orthologous genes will vary between species depending upon the experimental evidence available, annotation completeness, and fundamental differences in biology. Please take note of any aspects of the gene's biology that are not represented in the existing GO annotations.
Gene Ontology Consortium Amigo Browser: Many Species
RGD Browser: Rat
Community Input Section
Examine the GO annotations for IL1A, using the links above, and tell us about aspects of its biology that are still unannotated by editing the wiki page directly. GO curators are notified when particular gene pages are changed and will act upon your contributed information to create new GO annotations.
Please duplicate and complete the following sections:
Gene function, process, cellular location or interacting partner (as a list or short summary): nuclear localization of pre-IL-1alpha depends on the binding to HAX-1
Method or evidence used to support the annotation (eg enzyme assay, flow cytometry, immunoprecipitation, mutant phenotype, etc.): Immunoprecipitation
Supporting Literature Reference (PubMedID or citation): PMID: 16971486
Contact email address (optional): Ruth Lovering ruth@GOA.co.uk
Link to example of submitted GO annotation