FlyBase December 2016
1. Staff working on GOC tasks
Helen Attrill (GO curator/literature curator) 0.3 FTE
Giulia Antonazzo (GO curator/literature curator) 0.1 FTE
Alix Rey (GO curator/literature curator) 0.2 FTE
Steven Marygold (Literature curator) 0.1 FTE
Gillian Millburn (Literature curator) 0.2 FTE
Kathleen Falls (Developer)
Josh Goodman (Web Developer)
2. Annotation progress
Table showing progress in annotating Drosophila localized genes Nov 2015 - Nov 2016 (FB2015_61 - FB2016_06)
Nov 14 | Nov 15 | % change | % of total genes | |
---|---|---|---|---|
Total number of localized genes (excluding pseudogenes) | 17382 | 17747 | +2.1% | |
Localized genes with no GO annotation | 4692 | 4941 | -5.3% | 27.8% |
Localized genes with any GO annotation | 12690 | 12806 | +0.9% | 73.0% |
Localized genes with 1 or more term based on experimental evidence | 6095 | 6724 | +10.3% | 37.8% |
Localized genes with other non-IEA, non-ND evidence | 3830 | 2420 | -36.8% | 13.6% |
Localized genes with only IEA evidence | 991 | 1864 | +88.1% | 10.5% |
Localized genes with only ND evidence | 1840 | 1798 | -2.3% | 10.1% |
Table showing total annotation progress for localized genes Nov 2014 - Nov 2015 (FB2014_06 - FB2015_05)
November 2015 | November 2016 | % change | |
---|---|---|---|
GO Biological Process (BP) annotations | 48093 (8360 genes) | 46131 (4879 genes) | -4.1% |
GO Molecular Function (MF) annotations | 28273 (9121 genes)) | 22742 (5393 genes) | -4.1% |
GO Cellular Component (CC) annotations | 24219 (8360 genes) | 21064 (2508 genes) | -13.0% |
Total annotations for localized genes | 100585 | 89937 | -10.6% |
Notes: This year FlyBase has focussed on a major revision of its GO annotation set. Historic annotation sets (pre-2008) were reviewed for quality (i.e. correctness), traceability and adherence to current guidelines. Those sets that were deemed to not meet the criteria were removed. This included annotations made from conference abstracts, based on protein and DNA sequence records, various Celera project annotations, personal communications, FlyBase analysis 1992-. This saw over 10,000 annotations removed.
FlyBase is in the process of implementing a robust import pipeline to bring in external annotations on a sustainable basis. (Perviously this was only performed on an ad hoc basis.) This includes annotations from the GO PAINT project, which will fill many of the 'holes' left by the clean up of the annotation set.