GO-CAM Conference Call - 2019-01-15

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Revision as of 08:14, 15 January 2019 by Stacia (talk | contribs) (Minutes)

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Meeting URL


  • From 2019-01-07 annotation conference call:
    • Import of whole genomes
      • Working meeting at Berkeley the end of this month
      • WormBase and MGI will be the first genome annotation sets to be imported
        • gp2term relations
        • evidence and annotation extensions
        • search, display, editing
        • gpad output
        • overall data flow
        • documentation
    • Continued discussion of modeling questions
      • Annotation of protein complexes and their respective members
      • Instance-level representation
        • When to annotate to the same 'instance' of a biological process vs different 'instances'?
        • Implications for curator workflow
      • Modeling from multiple species
        • Creating a model for one species when the evidence derives from experiments in multiple species
        • Creating models for processes that involve more than one species
    • Import of Reactome pathways
      • Glycolysis
      • MAPK
      • BMP
      • Wnt
      • ER-UPR
      • GPI synthesis
      • Size limitations and delineation of 'models'
        • How to 'stitch' or connect large models in a consistent manner that allows us to represent dependencies (upstream, downstream) in a biologically meaningful way that is also computationally amenable
    • Model manipulation
      • Generation and use of templates
      • Merging models
      • Copying and/or re-using annotations


  • On call: Barbara, Chris, David, Dustin, Elena, Giulia, Harold, Helen, Kimberly, Laurent-Philippe, Marie-Claire, Petra, Rob, Ruth, Sabrina, Seth, Stacia, Suzi A