Guidelines for creating a Regulation Term
See Ontology_Editors_Daily_Workflow for creating branches and basic Protégé instructions.
- To create a ‘positive regulation of x’ or ‘negative regulation of x’ term, the parent ‘regulation of x’ term must first be created.
- To create anew term, here, the parent
regulation
term, make sure the ‘Asserted view’ is active (not the ‘Inferred view’). - In the
Protege classes view
, navigate tobiological regulation
. - Click on the add subclass button at the top left corner.
- In the pop-up window add the name of the new regulation term
regulation of target process
. The identifier should auto-populate. Click the button to add the term. - Enter the appropriate information for namespace, definition, synonyms, etc. in the obo editing view as described in the ‘Creating a New Ontology Term’ Section.
- Standard definitions for regulation terms:
Regulation: Any process that modulates the frequency, rate or extent of [process]
Positive regulation: Any process that activates or increases the frequency, rate or extent of [process]
Negative regulation: Any process that stops, prevents or reduces the frequency, rate or extent of [process]
- Create a logical definition for the term:
biological regulation and (negatively/positively)regulates some target process
. - Remove the asserted
biological regulation
parent. - Run the reasoner to be sure that reasoning results in the correct inferred parents.
- Save changes.
See Ontology_Editors_Daily_Workflow for commit, push and merge instructions.
Review Status
Last reviewed: May 24, 2017 Back to: Ontology Editing Guide