Heart Development workshop (Archived)
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Please suggest agenda items, relevant papers and other information relating to heart development GO terms that you would like discussed at this workshop, to enable us to form an agenda.
Participants
GO annotators | GO Editors | Heart Development Experts |
---|---|---|
Dr Varsha Khodiyar (BHF-UCL) Dr Ruth Lovering (BHF-UCL) Dr Doug Howe (ZFIN) Dr Susan Tweedie (Flybase) Dr Yasmin Alam-Faruque (GOA) |
Dr Tanya Berardini Dr David Hill |
Professor Shoumo Bhattacharya Professor Pete Scambler Dr Ross Breckenridge Dr Paul Riley |
Location
Tuesday 22nd September 2009, 9:15am to 5pm
PLEASE NOTE CHANGE OF VENUE
Rockefeller building, room 339 UCL map Google map
Directions from Rockefeller entrance to the meeting room - Go up to the 3rd floor in the lift in front of you. As you leave the lift on the third floor, bear left up the steps and through the door. Follow the corridor round to room 339.
Programme
9:15am | Coffee and breakfast pastries | |
9:30am | Welcome and introduction | Varsha |
9:35am | Introduction to GO | David |
9:45am | Check terms are applicable across Bilateria * heart * blood * vessels * SF - blood circulation |
Susan |
10:15am | Cardiac precursor tissues and cells * Development of primary and secondary heart fields * cardiac muscle cell specification/differentiation/development * cardiac endothelial cell specification/differentiation/development * SF - symmetry/asymmetry, heart cone, precursor cell differentiation, endocardium, heart field |
|
11am | Coffee break | |
11:45am | Cardiac cell migration, Heart morphogenesis * morphogenic and migratory changes to those cell populations as they move towards formation of the heart tube * L/R patterning * neural crest contribution to the heart * SF - cell migration, heart tube, heart looping and jogging |
|
12:30pm | Lunch at Ask on Grafton Way. Menu | |
2pm | Continue with Cardiac cell migration, Heart morphogenesis | |
2:45pm | Heart structure formation * heart chamber, septum, trabeculae, valves * SF - heart hypertrophy, septum morphogenesis, chamber development, heart valves |
|
3:45pm | Coffee break | |
4pm | Cardiac conduction * development of the electrical signaling systems of the heart * SF - cardiac conduction |
|
5pm | Close |
Minutes
Minutes_Heart_Development_workshop
Current Heart Development Ontology Terms
The currently available heart development process ontology can be viewed here chart (May 2009)
The 38 GO IDs used to create this graph:
GO:0001947 GO:0003007 GO:0007507 GO:0007510 GO:0007512 GO:0007513 GO:0010002 GO:0035050 GO:0035051 GO:0035052 GO:0035053 GO:0035054 GO:0042684 GO:0042685 GO:0048738 GO:0048739 GO:0055003 GO:0055004 GO:0055005 GO:0055006 GO:0055007 GO:0055008 GO:0055009 GO:0055010 GO:0055011 GO:0055012 GO:0055014 GO:0055015 GO:0055017 GO:0060038 GO:0060214 GO:0060317 GO:0060347 GO:0060379 GO:0060411 GO:0060412 GO:0060413 GO:0060419
heart morphological structure development (19 terms) chart:
GO:0001947 GO:0003007 GO:0007507 GO:0007512 GO:0035050 GO:0035054 GO:0048738 GO:0048739 GO:0055008 GO:0055009 GO:0055010 GO:0055017 GO:0060214 GO:0060317 GO:0060347 GO:0060411 GO:0060412 GO:0060413 GO:0060419
differentiation of specific cardiac cell types (20 terms) chart:
GO:0007510 GO:0007513 GO:0010002 GO:0035051 GO:0035052 GO:0035053 GO:0042684 GO:0042685 GO:0055003 GO:0055004 GO:0055005 GO:0055006 GO:0055007 GO:0055011 GO:0055012 GO:0055014 GO:0055015 GO:0060038 GO:0060317 GO:0060379
Relevant papers and other resources
Zebrafish papers
Recent review on signaling involved in development of the second heart field - Rochais et al., 2009 PMID:19390062
Differences in cardiomyocyte differentiation b/t mice and zebrafish - de Pater et al., 2009 PMID:19395641
Zebrafish mutants affecting several aspects of heart tube development and morphogenesis - Rohr et al., 2006 PMID:16319113
Review of Zebrafish heart development, covers L/R patterning, morphogenesis - Bakkers et al., 2009 PMID:19371733
Good cartoon of zebrafish heart anatomy - Hu et al., 2001 PMID:11505366
Zebrafish genetics and vertebrate heart formation Stainier 2001 PMID:11253067
Neural Crest papers
Another key role for the cardiac neural crest in heart development.Rosenquist TH and Finnell 2007 PMID:17098821
Fate of the mammalian cardiac neural crest.Jiang et al., 2000 PMID:10725237
Cardiac neural crest in zebrafish - Sato and Yost, 2003 PMID:12710962
Other reviews
Heart Development in Developmental Biology - Dev. Biology (Gilbert, 6th edition)
Signaling pathways controling second heart field development - Rochais et al., 2009 PMID:19390062
Origin and fate of cardiac mesenchyme - Snarr et al., 2008 PMID:18816864
Cardiac Progenitors and the Embryonic Cell Cycle - Goetz and Conlon, 2007 PMID:17712230
Cardiovascular Embryology Animations
Mouse Anatomy Browser - Heart
FMA human anatomy browser- Heart
Notes
1. Cardiac muscle cell development was covered by the muscle group, but it won't hurt to give it a review (David)
2. In GO, heart does indeed refer to the dorsal vessel of arthropods, but I'm not sure we will have time to cover it in this meeting other than to make sure we are not inconsistent with the representation of its development (David)
3. specific terms we need to incorporate into the ontology (Varsha)
* atrioventricular conduction (PMID:10587520 for annotation of NKX2-5 P52952)
* septum secundum development (PMID:10587520 for annotation of NKX2-5 P52952)