Immunology: Difference between revisions

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An immunology annotation group has formed to focus on the annotation of immunologically important genes.  This work follows on the extensive revision of the Gene Ontology to provide more comprehensive representation of immunologically important functions and processes.
[[Category:Immunology]]
<big>'''The Gene Ontology Consortium's Community Annotation Wiki for Immunology'''</big>


We are in the process of defining the sets of gene products of highest interest to immunology researchers.  These sets will be posted on ''immunological important gene sets'' pages.  We are also organizing this work in terms of ''immunological important biological processes'' pages. 
=='''Introduction'''==


Scientists are encouraged to provide input for specific genes or processes as these pages are developed.
In order to promote our work annotating genes of immunological interest using the Gene Ontology, we have set up a wiki to allow members of the community of experimental immunologists and other interested parties to review GO annotation of their genes of interest and provide us with additional information to guide our annotation efforts for these genes. '''Note that at present there is no dedicated funding to support the annotation of genes associated with immunological processes, although some annotation of these genes occurs as part of other annotation efforts.'''


[[immunologically important genes]]
The wiki consists of a set of gene-specific pages that each provide links to general information and existing GO annotation for a given human gene and its orthologs in other species.  A separate section of the gene page is set up for editing by users to provide us with information that we will then use to make additional GO annotations for that gene.  We are particularly interested in aspects of the biology for a particular gene that are not currently represented in its existing GO annotation.  '''Information regarding a particular gene in any species is welcome.'''


[[immunologically important biological processes]]
A second set of pages lists important immunological processes, again providing links to existing GO annotation and having a section for editing by users to provide information that may lead to additional GO annotation.
 
Our focus on immunology annotation follows upon an extensive revision of the Gene Ontology to provide a more comprehensive representation of immunologically important processes [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17267433&query_hl=1&itool=pubmed_docsum (1)].  You may explore GO terms for immune system processes using the GO Consortium's [http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?xpand=GO:0002376&search_constraint=terms&query=GO:0002376&view=details&show_associations=list Amigo Browser].
 
Scientists are encouraged to provide input for specific genes or processes to the gene or process specific pages.  We will review information provided through the wiki on a timely basis, and notify users of how their contributions have resulted in GO annotations.
 
=='''The Wiki Pages'''==
 
[[Immunologically Important Genes]]
 
[[Immunologically Important Biological Processes]]
 
[[Explanation of Gene Prioritization]]
 
[[Suggestions for New GO Terms Related to Immunology]]
 
[[Background and Instructions]]
 
[[Related GO Immunology Publications]]
 
[[Immunology Wiki Credits|Credits]]
 
Example of a gene page: IL1A[http://wiki.geneontology.org/index.php/Example_GO_annotation_submission]

Revision as of 11:57, 5 May 2014

The Gene Ontology Consortium's Community Annotation Wiki for Immunology

Introduction

In order to promote our work annotating genes of immunological interest using the Gene Ontology, we have set up a wiki to allow members of the community of experimental immunologists and other interested parties to review GO annotation of their genes of interest and provide us with additional information to guide our annotation efforts for these genes. Note that at present there is no dedicated funding to support the annotation of genes associated with immunological processes, although some annotation of these genes occurs as part of other annotation efforts.

The wiki consists of a set of gene-specific pages that each provide links to general information and existing GO annotation for a given human gene and its orthologs in other species. A separate section of the gene page is set up for editing by users to provide us with information that we will then use to make additional GO annotations for that gene. We are particularly interested in aspects of the biology for a particular gene that are not currently represented in its existing GO annotation. Information regarding a particular gene in any species is welcome.

A second set of pages lists important immunological processes, again providing links to existing GO annotation and having a section for editing by users to provide information that may lead to additional GO annotation.

Our focus on immunology annotation follows upon an extensive revision of the Gene Ontology to provide a more comprehensive representation of immunologically important processes (1). You may explore GO terms for immune system processes using the GO Consortium's Amigo Browser.

Scientists are encouraged to provide input for specific genes or processes to the gene or process specific pages. We will review information provided through the wiki on a timely basis, and notify users of how their contributions have resulted in GO annotations.

The Wiki Pages

Immunologically Important Genes

Immunologically Important Biological Processes

Explanation of Gene Prioritization

Suggestions for New GO Terms Related to Immunology

Background and Instructions

Related GO Immunology Publications

Credits

Example of a gene page: IL1A[1]