Inferred from High Throughput Genetic Interaction (HGI): Difference between revisions
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'''HTP: Inferred from High Throughput Genetic Interaction''' | '''HTP: Inferred from High Throughput Genetic Interaction''' | ||
==Overview== | |||
The HGI evidence code is used for annotations based on high throughput experiments reporting the effects of perturbations in the sequence or expression of one or more genes or gene products. HGI is also used for high throughput experiments that interrogate functional interactions between two or more genes or gene products when co-expressed, for example, in a cell line. Additional uses of HGI include high throughput experiments in which the expression of one gene affects the phenotypic outcome of a mutation in another gene. | |||
The HGI evidence code requires curators enter a stable database identifier for the interacting entity in the With/From field of the Gene Association File (GAF). Independent interactors may be captured in the With/From field by separating each entry with a pipe. If the interaction experiment involves multiple perturbations simultaneously, e.g. triply mutant strains, then the respective interactors are separated with a comma. | |||
No data at: | No data at: | ||
Revision as of 05:30, 26 February 2018
HTP: Inferred from High Throughput Genetic Interaction
Overview
The HGI evidence code is used for annotations based on high throughput experiments reporting the effects of perturbations in the sequence or expression of one or more genes or gene products. HGI is also used for high throughput experiments that interrogate functional interactions between two or more genes or gene products when co-expressed, for example, in a cell line. Additional uses of HGI include high throughput experiments in which the expression of one gene affects the phenotypic outcome of a mutation in another gene.
The HGI evidence code requires curators enter a stable database identifier for the interacting entity in the With/From field of the Gene Association File (GAF). Independent interactors may be captured in the With/From field by separating each entry with a pipe. If the interaction experiment involves multiple perturbations simultaneously, e.g. triply mutant strains, then the respective interactors are separated with a comma.
No data at: