LAG3: Difference between revisions
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[[Immune Gene Page L|Return to Listing of Immune Related Genes Beginning with 'L']] | |||
== '''Information and Links''' == | |||
<big>'''LAG3''' ''lymphocyte-activation gene 3''</big> | |||
'''Also known as: '''Lag3, CD223, LAG-3, Ly66 | |||
<div align="right"><small>Nomenclature accurate as of April 27, 2007</small></div> | |||
'''Gene Details: '''[http://www.genenames.org/data/hgnc_data.php?hgnc_id=6476 HGNC] (human) [http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:106588 MGI] (mouse) [http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1302990 RGD] (rat) | |||
'''Entrez Gene Pages: '''[http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3902&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum Human] [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=16768&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum Mouse] [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=297596&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum Rat] [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=515155&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum Cow] | |||
'''<u>Orthology Predictions</u>''' | |||
Through [http://www.informatics.jax.org/searches/homology_report.cgi?id=MGI:106588 MGI] (human and other mammalian species) | |||
Through [http://www.genenames.org/cgi-bin/hcop.pl?species_pair=Human+and+Any+species&column=symbol&query=LAG3&Search=Search HGNC/HCOP] (vertebrate and invertebrate orthologs) | |||
== '''Existing GO Annotation''' == | |||
Use the links below as well as the links to the gene information pages above to check existing GO annotation for '''LAG3'''. | |||
GO annotation for a particular gene in a set of orthologous genes will vary between species depending upon the experimental evidence available, annotation completeness, and fundamental differences in biology. | |||
Please take note of any aspects of the gene's biology that are not represented in the existing GO annotations. | |||
'''Gene Ontology Consortium Amigo Browser:''' [http://www.godatabase.org/cgi-bin/amigo/go.cgi?action=query&view=query&query=LAG3&search_constraint=gp Many Species] | |||
'''GOA QuickGO Browser: '''[http://www.ebi.ac.uk/ego/GSearch?query=P18627&mode=name_syno&ontology=all_ont Human] [http://www.ebi.ac.uk/ego/GSearch?query=Q61790&mode=name_syno&ontology=all_ont Mouse] [http://www.ebi.ac.uk/ego/GSearch?query=Q5BK54&mode=name_syno&ontology=all_ont Rat] | |||
'''MGI Browser: '''[http://www.informatics.jax.org/javawi2/servlet/WIFetch?page=markerGO&id=MGI:106588 Mouse] [http://www.informatics.jax.org/javawi2/servlet/WIFetch?page=GOOrthologyGraph&id=MGI:106588 Mouse-Human-Rat Comparative GO Graph] | |||
'''RGD Browser: '''[http://rgd.mcw.edu/tools/genes/gene_ont_view.cgi?id=1302990 Rat] | |||
== '''Community Input Section''' == | |||
Examine the GO annotations for '''LAG3''', using the links above, and tell us about aspects of its biology that are still unannotated by editing the wiki page directly. | |||
GO curators are notified when particular gene pages are changed and will act upon your contributed information to create new GO annotations. | |||
Supporting literature may be found through the GeneRIFs on the Entrez Gene pages above, or directly through [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed PubMed] or [http://www.ebi.ac.uk/citexplore/ CiteXplore] | |||
'''Please duplicate and complete the following sections:''' | |||
________________________________________________________ | |||
Gene function, process, cellular location or interacting partner (as a list or short summary): | |||
Method or evidence used to support the annotation (eg enzyme assay, flow cytometry, immunoprecipitation, mutant phenotype, etc.): | |||
Supporting Literature Reference (PubMedID or citation): | |||
Contact email address (optional): | |||
Additional notes: | |||
________________________________________________________ | |||
'''<big>Thank you</big>''' | |||
''<big>[[Example GO annotation submission|Link to example of submitted GO annotation]]</big>'' | |||
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'''<big>[[Help:Editing|Editing Help]]</big>'''<div align="right"><small>(7)</small></div> |
Revision as of 01:11, 5 May 2007
Return to Listing of Immune Related Genes Beginning with 'L'
Information and Links
LAG3 lymphocyte-activation gene 3
Also known as: Lag3, CD223, LAG-3, Ly66
Gene Details: HGNC (human) MGI (mouse) RGD (rat)
Entrez Gene Pages: Human Mouse Rat Cow
Orthology Predictions
Through MGI (human and other mammalian species)
Through HGNC/HCOP (vertebrate and invertebrate orthologs)
Existing GO Annotation
Use the links below as well as the links to the gene information pages above to check existing GO annotation for LAG3.
GO annotation for a particular gene in a set of orthologous genes will vary between species depending upon the experimental evidence available, annotation completeness, and fundamental differences in biology. Please take note of any aspects of the gene's biology that are not represented in the existing GO annotations.
Gene Ontology Consortium Amigo Browser: Many Species
GOA QuickGO Browser: Human Mouse Rat
MGI Browser: Mouse Mouse-Human-Rat Comparative GO Graph
RGD Browser: Rat
Community Input Section
Examine the GO annotations for LAG3, using the links above, and tell us about aspects of its biology that are still unannotated by editing the wiki page directly. GO curators are notified when particular gene pages are changed and will act upon your contributed information to create new GO annotations.
Supporting literature may be found through the GeneRIFs on the Entrez Gene pages above, or directly through PubMed or CiteXplore
Please duplicate and complete the following sections:
________________________________________________________
Gene function, process, cellular location or interacting partner (as a list or short summary):
Method or evidence used to support the annotation (eg enzyme assay, flow cytometry, immunoprecipitation, mutant phenotype, etc.):
Supporting Literature Reference (PubMedID or citation):
Contact email address (optional):
Additional notes:
________________________________________________________
Thank you
Link to example of submitted GO annotation