LEGO May 18, 2015: Difference between revisions
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** GTP-bound Tem1 localizes to the spindle pole body | ** GTP-bound Tem1 localizes to the spindle pole body | ||
** Tem1 and Cdc15 physically interact in a manner dependent on Tem1's GTP-binding domain | ** Tem1 and Cdc15 physically interact in a manner dependent on Tem1's GTP-binding domain | ||
** Tem1 is required for Cdc15 localization to the spindle pole body | ** Tem1 is required for Cdc15 localization to the spindle pole body during late anaphase | ||
** Cdc15 | ** Cdc15 | ||
[[Category:LEGO]] | [[Category:LEGO]] | ||
Revision as of 10:47, 15 May 2015
Action Items from May 4, 2015 Call
- Make a github ticket for adding IntAct protein complexes to Noctua. [DONE]
- Heiko will let Seth know that curators may add feature requests, but these are not immediate needs.
- David, Kimberly, and Rama will review their March paper models to compare with Paul's version.
- Continue to work on LEGO model for the April consistency exercise - http://www.ncbi.nlm.nih.gov/pubmed/24349431
March Paper - Modeling the Mitotic Exit Network
- Additional reading: The Mitotic Exit Network: new turns on old pathways.
- Steps/functions in pathway to model:
- GTP-bound Tem1 localizes to the spindle pole body
- Tem1 and Cdc15 physically interact in a manner dependent on Tem1's GTP-binding domain
- Tem1 is required for Cdc15 localization to the spindle pole body during late anaphase
- Cdc15