Difference between revisions of "Manager 5November2014"
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(Created page with " =Agenda= ===Transferring annotations to geneproducts in other strains=== <pre> Hi Rama, I have a quick question for you regarding how your group manually maps curated GO ann...")
Revision as of 14:09, 4 November 2014
Transferring annotations to geneproducts in other strains
Hi Rama, I have a quick question for you regarding how your group manually maps curated GO annotations from one bacterial strain to another of the same species. I was wondering if the best practice would be to use the same evidence code (e.g. IDA) for cases where I was looking at conservative ortholog calls for genes of the same species, different strains? Or should I use the ISO code and the with_from value (e.g. PseudoCAP:PA1777) to indicate the strain the function/process was observed in? I used the former approach when I originally did some GO mapping to Pseudomonas aeruginosa strains in our database, but I'm now leaning toward the latter approach in order to make the logic behind the call more transparent. Do you have any opinion on which approach is best? Thanks for any help you can offer! Geoff