Difference between revisions of "Manager 5November2014"

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(Transferring annotations to geneproducts in other strains)
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===Trello board===

Revision as of 14:34, 4 November 2014


Transferring annotations to geneproducts in between strains

Hi Rama,
I have a quick question for you regarding how your group manually maps curated GO annotations 
from one bacterial strain to another of the same species.
I was wondering if the best practice would be to use the same evidence code (e.g. IDA) for 
cases where I was looking at conservative ortholog calls for genes of the same species, different strains? 
Or should I use the ISO code and the with_from value (e.g. PseudoCAP:PA1777) to indicate the strain the 
function/process was observed in? I used the former approach when I originally did some GO mapping to 
Pseudomonas aeruginosa strains in our database, but I'm now leaning toward the latter approach in order to 
make the logic behind the call more transparent. 
Do you have any opinion on which approach is best?
Thanks for any help you can offer!

Trello board